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电视辅助胸腔镜手术(VATS)术后疼痛的特征及疼痛相关因素:中国国家癌症中心的经验

Characteristics of Postoperative Pain After VATS and Pain-Related Factors: The Experience in National Cancer Center of China.

作者信息

Tong Yao, Wei Peipei, Wang Shuang, Sun Qiuying, Cui Yanzheng, Ning Ning, Chen Sitong, He Xin

机构信息

Department of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People's Republic of China.

出版信息

J Pain Res. 2020 Jul 21;13:1861-1867. doi: 10.2147/JPR.S249134. eCollection 2020.

Abstract

PURPOSE

No final conclusion has yet been reached on characteristics of postoperative pain and pain-related factors after video-assisted thoracoscopic surgery (VATS). This study was designed to explore features of acute severe pain and chronic post-surgical pain (CPSP), and the pain-related factors of VATS.

PATIENTS AND METHODS

Data of patients who underwent VATS for lung cancer in Cancer Hospital, Chinese Academy of Medical Sciences between March 2017 and January 2019 were reviewed in this retrospective study. A numerical rating scale (NRS) was used for evaluating the intensity of postoperative pain including no pain (NRS=0), mild pain (NRS=1-3), moderate pain (NRS=4-6), and severe pain (NRS=7-10). Pain intensity was assessed daily within a week after operation, and also evaluated at 3 months postoperatively.

RESULTS

One hundred and five (3.4%) of the 3072 patients enrolled experienced severe pain (NRS=7-10) on the 1st day after operation, and 17 (0.6%) on the 2nd day. Smoking history, three-port VATS, prolonged operation time, and without patient-controlled analgesia (PCA) were correlated to increased incidence of severe pain. Among all patients, 237 (7.7%) cases generated CPSP, and VATS type, operation time, duration of drainage, and severe pain on the 1st day were four independent risk factors related to CPSP.

CONCLUSION

Patients seemed to experience a lower incidence of acute severe pain and CPSP after VATS than traditional open surgery. Acute severe pain was correlated with smoking history, VATS type, operation time, and PCA; VATS type, operation time, duration of drainage, and severe pain on the 1st day postoperatively were four independent risk factors of CPSP.

摘要

目的

关于电视辅助胸腔镜手术(VATS)术后疼痛的特征及疼痛相关因素,尚未得出最终结论。本研究旨在探讨急性重度疼痛和慢性术后疼痛(CPSP)的特征以及VATS的疼痛相关因素。

患者与方法

本回顾性研究回顾了2017年3月至2019年1月在中国医学科学院肿瘤医院接受VATS治疗肺癌的患者数据。采用数字评分量表(NRS)评估术后疼痛强度,包括无痛(NRS = 0)、轻度疼痛(NRS = 1 - 3)、中度疼痛(NRS = 4 - 6)和重度疼痛(NRS = 7 - 10)。术后一周内每天评估疼痛强度,并在术后3个月进行评估。

结果

3072例入组患者中,105例(3.4%)在术后第1天经历重度疼痛(NRS = 7 - 10),17例(0.6%)在术后第2天经历重度疼痛。吸烟史、三孔VATS、手术时间延长以及未使用患者自控镇痛(PCA)与重度疼痛发生率增加相关。在所有患者中,237例(7.7%)发生CPSP,VATS类型、手术时间、引流持续时间和术后第1天的重度疼痛是与CPSP相关的四个独立危险因素。

结论

与传统开放手术相比,VATS术后患者急性重度疼痛和CPSP的发生率似乎较低。急性重度疼痛与吸烟史、VATS类型、手术时间和PCA相关;VATS类型、手术时间、引流持续时间和术后第1天的重度疼痛是CPSP的四个独立危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8140/7382587/154bcb352455/JPR-13-1861-g0001.jpg

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