Jiang Chen, Chen Qiong, Xie Mingxuan
Department of Gerontology and Respirology, Xiangya Hospital, Central South University, Changsha, China.
National Clinical Research Centre for Geriatric Disorders, Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, China.
Tob Induc Dis. 2020 Jul 14;18:60. doi: 10.18332/tid/123845. eCollection 2020.
Smoking is relevant to infectious diseases resulting in increased prevalence and mortality. In this article, we aim to provide an overview of the effects of smoking in various infections and to explain the potential mechanisms. We searched PubMed and other relevant databases for scientific studies that explored the relationship between smoking and infection. The mechanisms of susceptibility to infection in smokers may include alteration of the structural, functional and immunologic host defences. Smoking is one of the main risk factors for infections in the respiratory tract, digestive tract, reproductive tract, and other systems in humans, increasing the prevalence of HIV, tuberculosis, SARS-CoV, and the current SARS-CoV-2. Smoking cessation can reduce the risk of infection. Smoking increases the incidence of infections and aggravates the progress and prognosis of infectious diseases in a dose-dependent manner. Smoking cessation promotion and education are the most practical and economical preventive measures to reduce aggravation of disease infection owing to tobacco use.
吸烟与传染病相关，会导致患病率和死亡率上升。在本文中，我们旨在概述吸烟在各种感染中的影响，并解释潜在机制。我们在PubMed和其他相关数据库中搜索了探索吸烟与感染之间关系的科学研究。吸烟者易感染的机制可能包括宿主结构、功能和免疫防御的改变。吸烟是人类呼吸道、消化道、生殖道及其他系统感染的主要危险因素之一，会增加艾滋病毒、结核病、SARS-CoV以及当前的SARS-CoV-2的患病率。戒烟可降低感染风险。吸烟会增加感染发生率，并以剂量依赖的方式加重传染病的进展和预后。促进戒烟的宣传和教育是减少因烟草使用导致疾病感染加重的最切实可行且经济的预防措施。
