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空气污染与癌症之间的关联:系统评价的争议性证据。

The association between air pollution and cancers: controversial evidence of a systematic review.

机构信息

Health in Emergency and Disaster Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Department of Nursing, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Environ Sci Pollut Res Int. 2020 Nov;27(31):38491-38500. doi: 10.1007/s11356-020-10377-z. Epub 2020 Aug 7.

DOI:10.1007/s11356-020-10377-z
PMID:32767014
Abstract

There are inconsistent reports on the association between air pollution and cancers. This systematic review was, therefore, conducted to ascertain the relationship between air pollution and some cancers. This is a systematic review study, which all articles published in this area were extracted from January 1, 1950 to December 31, 2018 from Web of Science, PubMed, Scopus, Cochrane Library, MEDLINE, EMBASE, Science Direct, Google scholar. Searching was performed independently by two search-method experts. The required data were extracted from the articles by an author-made questionnaire. Forty-eight articles were investigated. Evidence linking air pollution to some cancers is limited. Leukemia had the highest association with exposure to various air pollutants and bladder cancer had the lowest association. It is noteworthy that the specific type of pollutants in all studies was not specified. Based on the findings, the results are contradictory, and the role of air pollution in some cancers cannot be supported. Accordingly, studies are recommended to be performed at the individual level or multifactorial studies to specifically investigate the relationship between air pollution and these types of cancers. In this way, the role of air pollution in the incidence of these cancers can be determined more accurately.

摘要

关于空气污染与癌症之间的关联,现有报告结果并不一致。因此,本系统综述旨在明确空气污染与某些癌症之间的关系。这是一项系统综述研究,从 Web of Science、PubMed、Scopus、Cochrane Library、MEDLINE、EMBASE、Science Direct 和 Google Scholar 等数据库中提取了自 1950 年 1 月 1 日至 2018 年 12 月 31 日期间发表的该领域的所有文章。两名检索方法专家独立进行检索。作者自制问卷从文章中提取所需数据。共调查了 48 篇文章。有证据表明,空气污染与某些癌症之间存在关联。白血病与接触各种空气污染物的关联度最高,膀胱癌的关联度最低。值得注意的是,所有研究中都没有具体说明特定类型的污染物。基于这些发现,结果存在矛盾,不能支持空气污染与某些癌症之间存在关联。因此,建议开展个体水平或多因素研究来专门调查空气污染与这些类型癌症之间的关系,以便更准确地确定空气污染在这些癌症发病中的作用。

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