College of Stomatology, Chongqing Medical University, Chongqing, China.
Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China.
J Clin Periodontol. 2020 Oct;47(10):1201-1208. doi: 10.1111/jcpe.13355. Epub 2020 Aug 26.
Building on previous psychometric work, we aimed to further assess the minimally important difference (MID) of the Oral Health Impact Profile for Chronic Periodontitis (OHIP-CP).
In total, 240 consecutive patients with chronic periodontitis were recruited in the study. The OHIP-CP was completed at baseline and after six weeks. Methodology testing included the confirmatory factor analysis (CFA) and MID. Confirmatory factor analysis (CFA) was performed to assess the fit of the previously proposed three-factor model. The MID of this questionnaire was determined by applying anchor-based and distribution-based approaches.
The CFA supported a three-factor model for the OHIP-CP with acceptable fit to the data. The fit indices were χ /df = 2.231, GFI = 0.935, TLI = 0.969 and CFI = 0.976, RMSEA = 0.076. The OHIP-CP scores showed significant improvements after treatment (p < .001). The anchor-based MIDs of OHIP-CP for "oral function restriction," "oral pain" and "psychological and social impact," and total score were 2, 1, 4 and 7 points, respectively. The effect sizes (ES) and standardized response mean (SRM) for the OHIP-CP were moderate to large.
The MID of the OHIP-CP is recommended for interpreting clinically meaningful change in oral health-related quality of life (OHRQoL) over time.
在前瞻性心理测量学工作的基础上，我们旨在进一步评估慢性牙周炎口腔健康影响量表（OHIP-CP）的最小临床重要差异（MID）。
本研究共纳入 240 例慢性牙周炎患者。患者在基线时和 6 周后完成 OHIP-CP 量表。方法学测试包括验证性因子分析（CFA）和 MID。验证性因子分析（CFA）用于评估先前提出的三因素模型的拟合度。该问卷的 MID 通过应用基于锚定和基于分布的方法来确定。
CFA 支持 OHIP-CP 的三因素模型，数据拟合度可接受。拟合指数为 χ /df=2.231，GFI=0.935，TLI=0.969，CFI=0.976，RMSEA=0.076。治疗后 OHIP-CP 评分显著改善（p<0.001）。OHIP-CP 的“口腔功能受限”、“口腔疼痛”和“心理社会影响”以及总分的基于锚定的 MID 分别为 2、1、4 和 7 分。OHIP-CP 的效应大小（ES）和标准化反应均值（SRM）为中等到较大。
推荐使用 OHIP-CP 的 MID 来解释口腔健康相关生活质量（OHRQoL）随时间的临床有意义的变化。
