Department of Interventional Ultrasound, Xianyang Central Hospital, Xianyang, Shaanxi, China.
Department of Orthopedics, Xianyang Central Hospital, Xianyang, Shaanxi, China.
Ultrasound Med Biol. 2020 Nov;46(11):2972-2978. doi: 10.1016/j.ultrasmedbio.2020.06.024. Epub 2020 Aug 4.
Our objectives were to measure the relationships between conventional ultrasound features, strain elastography in breast cancer and Ki-67 index and to identify parameters that predict Ki-67 index. We included 181 lesions of 178 patients who underwent surgery for breast cancer at Xianyang Central Hospital. In multivariate logistic regression analysis, strain elastography and axillary-node metastasis showed significant Ki-67 index values; the overall theoretical prediction percentage correct was 75.7%. Strain elastography showed that the median Ki-67 index in the hard group was higher than that in the soft group, and the Ki-67 index increased with increasing elasticity score. This finding may guide ultrasound-guided breast tumor biopsy for selection of puncture regions. The combined use of the Ki-67 index for strain-elastography prediction and puncture-biopsy pathology reports may increase the accuracy of clinical treatment.
我们的目的是测量常规超声特征、乳腺癌应变弹性成像与 Ki-67 指数之间的关系，并确定预测 Ki-67 指数的参数。我们纳入了在咸阳市中心医院接受乳腺癌手术的 178 例患者的 181 个病灶。在多变量逻辑回归分析中，应变弹性成像和腋窝淋巴结转移显示出与 Ki-67 指数显著相关；总体理论预测准确率为 75.7%。应变弹性成像显示，硬组的中位 Ki-67 指数高于软组，且 Ki-67 指数随弹性评分的增加而增加。这一发现可能有助于指导超声引导下乳腺肿瘤活检选择穿刺区域。联合使用 Ki-67 指数进行应变弹性成像预测和穿刺活检病理报告可能会提高临床治疗的准确性。
