Department of Ultrasonic, The Second Affiliated Hospital of Mudanjiang Medical University, Mudanjiang 157009, China.
Department of Anesthesiology, The Second Affiliated Hospital of Mudanjiang Medical University, Mudanjiang 157009, China.
Comput Math Methods Med. 2022 Jun 3;2022:8066289. doi: 10.1155/2022/8066289. eCollection 2022.
This research was aimed at investigating the role of ultrasound elastography (UE) in evaluating the properties of axillary lymph nodes in breast cancer and exploring the influencing factors of lymph node metastasis in breast cancer patients. Routine ultrasonography (US) and UE were performed for 160 breast cancer patients. 80 cases were in the group with lymph node metastasis, and the other 80 were in the nonlymph node metastasis group. The sensitivity, specificity, and accuracy of the two ultrasound examinations were compared, the receiver-operator characteristic (ROC) curves were drawn, and the influencing factors of lymph node metastasis were analyzed. The sensitivity, specificity, and accuracy of UE in diagnosing axillary lymph nodes of breast cancer were 97.22%, 95.45%, and 96.25%, respectively, which were markedly higher than those of routine US ( < 0.05). Cortical thickness, blood flow grade, blood flow type, and elasticity score had a greater impact on axillary lymph node metastasis of breast cancer. When cortical thickness ≥ 3 cm, blood flow was of 2-3 grades, blood flow was the peripheral/mixed type, and elasticity score was 3-4 points, these became risk factors for lymph node metastasis in breast cancer patients. UE was effective in diagnosing the property of lymph nodes and could evaluate lymph node metastasis in breast cancer patients. It had a good clinical value and was worthy of popularization and application.
本研究旨在探讨超声弹性成像（UE）在评估乳腺癌腋窝淋巴结性质中的作用，并探讨乳腺癌患者淋巴结转移的影响因素。对 160 例乳腺癌患者进行常规超声（US）和 UE 检查。80 例为淋巴结转移组，另 80 例为非淋巴结转移组。比较两种超声检查的敏感性、特异性和准确性，绘制受试者工作特征（ROC）曲线，并分析淋巴结转移的影响因素。UE 诊断乳腺癌腋窝淋巴结的敏感性、特异性和准确性分别为 97.22%、95.45%和 96.25%，明显高于常规 US（<0.05）。皮质厚度、血流分级、血流类型和弹性评分对乳腺癌腋窝淋巴结转移有较大影响。当皮质厚度≥3cm、血流为 2-3 级、血流为周边/混合型、弹性评分为 3-4 分时，这些成为乳腺癌患者淋巴结转移的危险因素。UE 对诊断淋巴结性质有效，可评估乳腺癌患者的淋巴结转移情况。具有良好的临床价值，值得推广应用。
