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穴位敷贴联合西药治疗变应性鼻炎的疗效与安全性:一项系统评价与Meta分析方案

The efficacy and safety of acupoint application combined with western medicine for allergic rhinitis: A protocol for systematic review and meta-analysis.

作者信息

Huang Yao, Fan Yihua, Tian Chunying, Zhang Mengni, Yang Shasha, Ji Yue, Zhang Qinxiu

机构信息

Hospital of Chengdu University of Traditional Chinese Medicine.

Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan province.

出版信息

Medicine (Baltimore). 2020 Aug 7;99(32):e21627. doi: 10.1097/MD.0000000000021627.

DOI:10.1097/MD.0000000000021627
PMID:32769925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7593031/
Abstract

BACKGROUND

Acupoint application combined with western medicine has been used for treating allergic rhinitis widely. However, the efficacy and safety of acupoint application combined with western medicine for allergic rhinitis are unclear. This study aims to evaluate the efficacy and safety of acupoint application combined with western medicine for allergic rhinitis.

METHODS

Randomized controlled trials of acupoint application combined with western medicine for allergic rhinitis will be searched in PubMed, EMbase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, WanFang, the Chongqing VIP Chinese Science and Technology Periodical Database, and China biomedical literature database from inception to July, 2020. And Baidu Scholar, Google Scholar, International Clinical Trials Registry Platform, and Chinese Clinical Trials Registry will be searched to obtain more relevant studies comprehensively. Two researchers will perform data extraction and risk of bias assessment independently. Statistical analysis will be conducted in RevMan 5.3.

RESULTS

This study will summarize the present evidence by exploring the efficacy and safety of acupoint application combined with western medicine for the treatment of allergic rhinitis.

CONCLUSIONS

The findings of the study will provide helpful evidence for the efficacy and safety of acupoint application combined with western medicine in the treatment of allergic rhinitis, facilitating clinical practice and further scientific studies.

ETHICS AND DISSEMINATION

The private information from individuals will not publish. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences.

OSF REGISTRATION NUMBER

DOI 10.17605/OSF.IO/NSGJH.

摘要

背景

穴位敷贴联合西药已广泛用于治疗变应性鼻炎。然而,穴位敷贴联合西药治疗变应性鼻炎的疗效和安全性尚不清楚。本研究旨在评价穴位敷贴联合西药治疗变应性鼻炎的疗效和安全性。

方法

检索PubMed、EMbase、Cochrane图书馆、Web of Science、中国知网、万方、维普中文科技期刊数据库和中国生物医学文献数据库中从建库至2020年7月关于穴位敷贴联合西药治疗变应性鼻炎的随机对照试验。并检索百度学术、谷歌学术、国际临床试验注册平台和中国临床试验注册中心以全面获取更多相关研究。两名研究人员将独立进行数据提取和偏倚风险评估。将在RevMan 5.3中进行统计分析。

结果

本研究将通过探讨穴位敷贴联合西药治疗变应性鼻炎的疗效和安全性来总结现有证据。

结论

本研究结果将为穴位敷贴联合西药治疗变应性鼻炎的疗效和安全性提供有益证据,促进临床实践和进一步的科学研究。

伦理与传播

不会公布个人隐私信息。本系统评价也不会涉及危及参与者权利。无需伦理批准。结果可能发表在同行评审期刊上或在相关会议上传播。

开放科学框架注册号

DOI 10.17605/OSF.IO/NSGJH。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d53a/7593031/b6fe33b27f11/medi-99-e21627-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d53a/7593031/b6fe33b27f11/medi-99-e21627-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d53a/7593031/b6fe33b27f11/medi-99-e21627-g002.jpg

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J Inflamm (Lond). 2020 Feb 10;17:4. doi: 10.1186/s12950-020-0236-9. eCollection 2020.
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Efficacy of acupuncture at three nasal acupoints plus acupoint application for perennial allergic rhinitis: A multicenter, randomized controlled trial protocol.针刺三鼻穴加穴位贴敷治疗常年性变应性鼻炎的疗效:一项多中心、随机对照试验方案。
Trials. 2020 Jan 28;21(1):110. doi: 10.1186/s13063-019-4039-3.
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Economic Burden of the Inadequate Management of Allergic Rhinitis and Urticaria in Asian Countries Based on the GA²LEN Model.
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Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis.中华医学会变态反应学分会变应性鼻炎诊断和治疗指南
Allergy Asthma Immunol Res. 2018 Jul;10(4):300-353. doi: 10.4168/aair.2018.10.4.300.
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