阿片类药物危机：系统科学研究的必要性。
The opioid crisis: need for systems science research.
作者信息
Jalali Mohammad S, Botticelli Michael, Hwang Rachael C, Koh Howard K, McHugh R Kathryn
机构信息
MGH Institute for Technology Assessment, Harvard Medical School, 101 Merrimac St, Suite 1010, Boston, MA, 02114, United States of America.
MIT Sloan School of Management, 100 Main St, Cambridge, MA, 02142, United States of America.
出版信息
Health Res Policy Syst. 2020 Aug 8;18(1):88. doi: 10.1186/s12961-020-00598-6.
Abstract
The opioid epidemic in the United States has had a devastating impact on millions of people as well as on their families and communities. The increased prevalence of opioid misuse, use disorder and overdose in recent years has highlighted the need for improved public health approaches for reducing the tremendous harms of this illness. In this paper, we explain and call for the need for more systems science approaches, which can uncover the complexities of the opioid crisis, and help evaluate, analyse and forecast the effectiveness of ongoing and new policy interventions. Similar to how a stream of systems science research helped policy development in infectious diseases and obesity, more systems science research is needed in opioids.
摘要
美国的阿片类药物泛滥对数百万民众及其家庭和社区造成了毁灭性影响。近年来，阿片类药物滥用、使用障碍及过量使用情况日益普遍，这凸显了改进公共卫生方法以减少这种疾病巨大危害的必要性。在本文中，我们解释并呼吁采用更多系统科学方法，这些方法能够揭示阿片类药物危机的复杂性，并有助于评估、分析和预测现行及新政策干预措施的有效性。正如一系列系统科学研究推动了传染病和肥胖症领域的政策制定一样，阿片类药物领域也需要更多的系统科学研究。
相似文献
1
The opioid crisis: need for systems science research.阿片类药物危机：系统科学研究的必要性。
Health Res Policy Syst. 2020 Aug 8;18(1):88. doi: 10.1186/s12961-020-00598-6.
2
The Opioid Epidemic: Challenge to Military Medicine and National Security.阿片类药物流行：对军事医学和国家安全的挑战。
Mil Med. 2020 Jun 8;185(5-6):e662-e667. doi: 10.1093/milmed/usz487.
3
The Other Three Waves: Re-assessing the Impact of Industry-Prescriber Relations on the Opioid Crisis.其他三个浪潮：重新评估产业-医师关系对阿片类药物危机的影响。
J Leg Med. 2021 Jan-Jun;41(1-2):47-81. doi: 10.1080/01947648.2021.1929589.
4
The opioid crisis: a contextual, social-ecological framework.阿片类药物危机：一个情境化的社会生态框架。
Health Res Policy Syst. 2020 Aug 6;18(1):87. doi: 10.1186/s12961-020-00596-8.
5
6
Epidemiology of the U.S. opioid crisis: the importance of the vector.美国阿片危机的流行病学：载体的重要性。
Ann N Y Acad Sci. 2019 Sep;1451(1):130-143. doi: 10.1111/nyas.14209. Epub 2019 Aug 4.
7
What would it really take to solve the overdose epidemic in the United States?要解决美国的药物过量流行问题，究竟需要付出什么？
Int J Drug Policy. 2024 Jun;128:104435. doi: 10.1016/j.drugpo.2024.104435. Epub 2024 May 9.
8
The Opioid Epidemic and Psychiatry: The Time for Action Is Now.阿片类药物流行与精神病学：现在是行动的时候了。
Psychiatr Serv. 2019 Dec 1;70(12):1168-1171. doi: 10.1176/appi.ps.201800582. Epub 2019 Sep 10.
9
Polysubstance use in the U.S. opioid crisis.美国阿片类药物危机中的多物质使用。
Mol Psychiatry. 2021 Jan;26(1):41-50. doi: 10.1038/s41380-020-00949-3. Epub 2020 Nov 13.
10
The Role of Emergency Medical Services in the Opioid Epidemic.紧急医疗服务在阿片类药物流行中的作用。
Prehosp Emerg Care. 2021 Jul-Aug;25(4):462-464. doi: 10.1080/10903127.2020.1810372. Epub 2020 Sep 4.
引用本文的文献
1
Social and behavioral correlates of sleep health among adults receiving medication treatment for opioid use disorder.接受阿片类物质使用障碍药物治疗的成年人睡眠健康的社会和行为相关因素。
Addict Res Theory. 2025 Aug 6. doi: 10.1080/16066359.2025.2530997.
2
Relative importance of socioecological domains to predicting opioid-involved mortality.社会生态领域对预测阿片类药物相关死亡率的相对重要性。
PLoS One. 2025 Jul 29;20(7):e0328286. doi: 10.1371/journal.pone.0328286. eCollection 2025.
3
Predicting fatal opioid-involved overdoses: A social-ecological framework matched to a linked-data warehouse.预测致命性阿片类药物过量用药：与关联数据仓库相匹配的社会生态框架。
Int J Drug Policy. 2025 Mar;137:104730. doi: 10.1016/j.drugpo.2025.104730. Epub 2025 Feb 9.
4
A Dynamic Model of Opioid Overdose Deaths in Canada during the Co-Occurring Opioid Overdose Crisis and COVID-19 Pandemic.加拿大阿片类药物过量危机与新冠疫情并发期间阿片类药物过量死亡的动态模型
Int J Environ Res Public Health. 2024 Apr 4;21(4):442. doi: 10.3390/ijerph21040442.
5
Psychosocial factors associated with overdose subsequent to Illicit Drug use: a systematic review and narrative synthesis.与非法药物使用后过量相关的心理社会因素：系统评价和叙述性综合。
Harm Reduct J. 2024 Apr 15;21(1):81. doi: 10.1186/s12954-024-00999-8.
6
Long-Term Effects of Increasing Buprenorphine Treatment Seeking, Duration, and Capacity on Opioid Overdose Fatalities: A Model-based Analysis.增加丁丙诺啡治疗寻求、持续时间和能力对阿片类药物过量死亡的长期影响：基于模型的分析。
J Addict Med. 2023;17(4):439-446. doi: 10.1097/ADM.0000000000001153. Epub 2023 Feb 28.
7
Opioid-related harms and care impacts of conventional and AI-based prescription management strategies: insights from leveraging agent-based modeling and machine learning.传统及基于人工智能的处方管理策略与阿片类药物相关危害及护理影响：基于主体建模和机器学习的见解
Front Digit Health. 2023 Jun 20;5:1174845. doi: 10.3389/fdgth.2023.1174845. eCollection 2023.
8
Reducing opioid use disorder and overdose deaths in the United States: A dynamic modeling analysis.减少美国阿片类药物使用障碍和过量死亡人数：一项动态建模分析。
Sci Adv. 2022 Jun 24;8(25):eabm8147. doi: 10.1126/sciadv.abm8147.
9
Modeling the evolution of the US opioid crisis for national policy development.为国家政策制定模拟美国阿片类药物危机的演变。
Proc Natl Acad Sci U S A. 2022 Jun 7;119(23):e2115714119. doi: 10.1073/pnas.2115714119. Epub 2022 May 31.
10
A Systematic Review of Simulation Models to Track and Address the Opioid Crisis.一项系统评价模拟模型以跟踪和解决阿片类药物危机。
Epidemiol Rev. 2022 Jan 14;43(1):147-165. doi: 10.1093/epirev/mxab013.
本文引用的文献
1
Evolution and Reproducibility of Simulation Modeling in Epidemiology and Health Policy Over Half a Century.半个多世纪以来流行病学和卫生政策模拟建模的演变和可重复性。
Epidemiol Rev. 2022 Jan 14;43(1):166-175. doi: 10.1093/epirev/mxab006.
2
The opioid crisis: a contextual, social-ecological framework.阿片类药物危机：一个情境化的社会生态框架。
Health Res Policy Syst. 2020 Aug 6;18(1):87. doi: 10.1186/s12961-020-00596-8.
3
Strengths and weaknesses of existing data sources to support research to address the opioids crisis.现有数据来源在支持应对阿片类药物危机研究方面的优势与不足。
Prev Med Rep. 2019 Nov 6;17:101015. doi: 10.1016/j.pmedr.2019.101015. eCollection 2020 Mar.
4
Evidence of Modeling Impact in Development of Policies for Controlling the Opioid Epidemic and Improving Public Health: A Scoping Review.在制定控制阿片类药物流行和改善公共卫生政策过程中建模影响的证据：一项范围综述
Subst Abuse. 2019 Aug 9;13:1178221819866211. doi: 10.1177/1178221819866211. eCollection 2019.
5
No Shortcuts to Safer Opioid Prescribing.安全开具阿片类药物处方没有捷径可走。
N Engl J Med. 2019 Jun 13;380(24):2285-2287. doi: 10.1056/NEJMp1904190. Epub 2019 Apr 24.
6
Dynamics of intervention adoption, implementation, and maintenance inside organizations: The case of an obesity prevention initiative.干预措施在组织内部的采用、实施和维持的动态变化：以肥胖预防倡议为例。
Soc Sci Med. 2019 Mar;224:67-76. doi: 10.1016/j.socscimed.2018.12.021. Epub 2018 Dec 23.
7
Prevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United States.预防美国处方类阿片药物滥用和预计的过量死亡。
JAMA Netw Open. 2019 Feb 1;2(2):e187621. doi: 10.1001/jamanetworkopen.2018.7621.
8
Modeling Health Benefits and Harms of Public Policy Responses to the US Opioid Epidemic.模拟美国阿片类药物泛滥公共政策反应的健康效益和危害。
Am J Public Health. 2018 Oct;108(10):1394-1400. doi: 10.2105/AJPH.2018.304590. Epub 2018 Aug 23.
9
Simulation Modeling and Metamodeling to Inform National and International HIV Policies for Children and Adolescents.模拟建模和变形建模以支持国家和国际针对儿童和青少年的艾滋病毒政策。
J Acquir Immune Defic Syndr. 2018 Aug 15;78 Suppl 1(1):S49-S57. doi: 10.1097/QAI.0000000000001749.
10
Dynamic model of nonmedical opioid use trajectories and potential policy interventions.非医疗用阿片类药物使用轨迹的动态模型及潜在政策干预措施
Am J Drug Alcohol Abuse. 2015;41(6):508-18. doi: 10.3109/00952990.2015.1043435. Epub 2015 May 18.
Zotero 插件