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接受阿片类物质使用障碍药物治疗的成年人睡眠健康的社会和行为相关因素。

Social and behavioral correlates of sleep health among adults receiving medication treatment for opioid use disorder.

作者信息

Sadler Lois S, Jeon Sangchoon, Ibrahim Ahmad, Barry Declan, Nwananji-Enwerem Uzoji, Scheinost Dustin, Yaggi Henry, Redeker Nancy S

机构信息

Yale University School of Nursing, Orange, CT, USA.

Yale School of Medicine, New Haven, CT, USA.

出版信息

Addict Res Theory. 2025 Aug 6. doi: 10.1080/16066359.2025.2530997.

Abstract

OBJECTIVES

Opioid use disorder (OUD) and its treatment (MOUD) are associated with altered sleep health. The purposes are to (1) describe profiles of sleep health among adults using medication for opioid use disorder (MOUD) and (2) examine the associations between multi-level individual, family, neighborhood, and social characteristics and sleep profiles. We hypothesized that poor quality of life, adverse life experiences, addiction behavior, dysfunctional family and social interactions, and negative neighborhood characteristics are associated with negative profiles of sleep health.

METHODS

This study comprised baseline analyses of the NIH/HEAL-funded CLOUDS study (Collaboration Linking Opioid Use Disorder and Sleep). We obtained self-report measures of sleep health and indicators of multi-level individual, family, and neighborhood factors. We identified sleep health profiles with K-means cluster analysis and examined the associations between these multi-level factors and sleep health profiles.

RESULTS

The sample included 165 participants (M age = 42, SD =11.4 years; = 73/42.2% female; = 37/22.4% Black or more than one race). We identified four sleep health profiles: Healthy sleep (Profile A; 30.3%); mild insomnia/late sleep timing (Profile B: 20%); clinical insomnia/long sleep (Profile C: 25.5%); and insomnia with excessive daytime sleepiness (Profile D: 23.6%). There were statistically significant differences across sleep profiles in physical and psychological health, addiction use and risk, family function, neighborhood esthetic quality, and perceptions of community support, with more adverse factors associated with poorer sleep health.

CONCLUSIONS

Research is needed to understand the causal directions of these relationships and promote multi-level interventions to promote sleep health.

摘要

目的

阿片类药物使用障碍(OUD)及其治疗(药物辅助治疗,MOUD)与睡眠健康改变有关。本研究旨在(1)描述使用药物辅助治疗阿片类药物使用障碍的成年人的睡眠健康状况,以及(2)研究个体、家庭、社区和社会等多层次特征与睡眠状况之间的关联。我们假设生活质量差、不良生活经历、成瘾行为、家庭和社会互动功能失调以及负面的社区特征与睡眠健康的负面状况相关。

方法

本研究包括对美国国立卫生研究院/帮助促进阿片类药物成瘾长期治疗、干预及减少毒品使用(HEAL)倡议资助的“阿片类药物使用障碍与睡眠的关联研究(CLOUDS)”的基线分析。我们获取了睡眠健康的自我报告测量数据以及个体、家庭和社区因素的多层次指标。我们通过K均值聚类分析确定了睡眠健康状况,并研究了这些多层次因素与睡眠健康状况之间的关联。

结果

样本包括165名参与者(年龄中位数 = 42岁,标准差 = 11.4岁;女性 = 73/42.2%;黑人或多种族 = 37/22.4%)。我们确定了四种睡眠健康状况:健康睡眠(A组;30.3%);轻度失眠/晚睡时间(B组:20%);临床失眠/睡眠时间长(C组:25.5%);以及伴有日间过度嗜睡的失眠(D组:23.6%)。在身体健康和心理健康、成瘾使用及风险、家庭功能、社区美观质量以及社区支持感知方面,不同睡眠状况之间存在统计学上的显著差异,更多不利因素与较差的睡眠健康相关。

结论

需要开展研究以了解这些关系的因果方向,并推动多层次干预措施以促进睡眠健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f26/12356222/cbcbe85cd09c/nihms-2102317-f0001.jpg

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