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本文引用的文献

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The Impact of Pharmacologic and Nonpharmacologic Interventions to Improve Physical Health Outcomes in People With Dementia: A Meta-Review of Meta-Analyses of Randomized Controlled Trials.药物和非药物干预对改善痴呆患者身体健康结局的影响:随机对照试验荟萃分析的元综述。
J Am Med Dir Assoc. 2020 Oct;21(10):1410-1414.e2. doi: 10.1016/j.jamda.2020.01.010. Epub 2020 Feb 19.
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High Diagnostic Accuracy of RT-QuIC Assay in a Prospective Study of Patients with Suspected sCJD.前瞻性研究疑似 sCJD 患者中 RT-QuIC 检测的高诊断准确性。
Int J Mol Sci. 2020 Jan 30;21(3):880. doi: 10.3390/ijms21030880.
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The Prevalence of Dementia: A Systematic Review and Meta-Analysis.痴呆症的患病率:系统评价和荟萃分析。
J Alzheimers Dis. 2020;73(3):1157-1166. doi: 10.3233/JAD-191092.
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Community engagement and dementia risk: time-to-event analyses from a national cohort study.社区参与与痴呆风险:一项全国队列研究的时依事件分析。
J Epidemiol Community Health. 2020 Jan;74(1):71-77. doi: 10.1136/jech-2019-213029. Epub 2019 Oct 29.
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Diagnosis and Management of Dementia: Review.痴呆的诊断与管理:综述。
JAMA. 2019 Oct 22;322(16):1589-1599. doi: 10.1001/jama.2019.4782.
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Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study.社交接触与痴呆和认知的关系:白厅 II 队列研究 28 年随访结果。
PLoS Med. 2019 Aug 2;16(8):e1002862. doi: 10.1371/journal.pmed.1002862. eCollection 2019 Aug.
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Cognitive impairment in depression: recent advances and novel treatments.抑郁症中的认知障碍:最新进展与新疗法
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认知障碍评估与管理。

Cognitive Impairment Evaluation and Management.

机构信息

Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA; Ralston House, Penn Memory Center, ATTN: Maria Crudele, 3615 Chestnut Street, Philadelphia, PA 19104-2612, USA.

Ralston House, Penn Memory Center, ATTN: Maria Crudele, 3615 Chestnut Street, Philadelphia, PA 19104-2612, USA; Division of Geriatrics, Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: https://twitter.com/jasonkarlawish.

出版信息

Med Clin North Am. 2020 Sep;104(5):807-825. doi: 10.1016/j.mcna.2020.06.007.

DOI:10.1016/j.mcna.2020.06.007
PMID:32773047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7416715/
Abstract

Clinicians should use a systematic approach to evaluating patients presenting with a concern for cognitive impairment. This approach includes interviewing a knowledgeable informant and performing a thorough mental status examination in order to determine the presence of functional impairments and the domains of cognition that are impaired. The results of this interview and examination determine the next steps of the diagnostic work-up. The pattern of cognitive impairment shapes the differential diagnosis. Treatment should address symptoms, and environmental, psychological, and behavioral interventions are essential.

摘要

临床医生应该采用系统的方法来评估出现认知障碍的患者。这种方法包括询问知情者并进行全面的精神状态检查,以确定是否存在功能障碍以及受损的认知领域。这些访谈和检查的结果决定了诊断工作的下一步。认知障碍的模式决定了鉴别诊断。治疗应该针对症状,环境、心理和行为干预至关重要。