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2020年手术在脑转移瘤管理中的地位是什么?

[What is the place of surgery in the management of brain metastases in 2020?].

作者信息

Cebula H, Todeschi J, Le Fèvre C, Antoni D, Ollivier I, Chibbaro S, Noël G, Proust F

机构信息

Service de neurochirurgie, hôpital de Hautepierre, 1, avenue Molière, 67098 Strasbourg, France.

Service de neurochirurgie, hôpital de Hautepierre, 1, avenue Molière, 67098 Strasbourg, France.

出版信息

Cancer Radiother. 2020 Oct;24(6-7):470-476. doi: 10.1016/j.canrad.2020.05.008. Epub 2020 Aug 6.

Abstract

Brain metastases are the most common intracranial tumors and are associated with a dismal prognosis. The management of patients with brain metastases has become more important because of the increased incidence of these tumours, the better treatment of the systemic disease and the improvement of surgical techniques. The treatment requires multidisciplinary approaches and become complex because of new emerging systemic therapy and advancements in neurosurgery and radiation oncology. The surgical treatment has an indispensable role to obtain a tissue diagnosis, in relieving intracranial effect mass and improving neurological status by improving induced encephalopathy. An understanding of the role and indications of the surgery in patients with metastatic brain lesions is essential for the effective management of this growing population.

摘要

脑转移瘤是最常见的颅内肿瘤,预后较差。由于这些肿瘤的发病率增加、全身疾病治疗的改善以及手术技术的进步,脑转移瘤患者的管理变得更加重要。治疗需要多学科方法,并且由于新出现的全身治疗以及神经外科和放射肿瘤学的进展而变得复杂。手术治疗在获得组织诊断、减轻颅内占位效应以及通过改善诱发性脑病来改善神经状态方面具有不可或缺的作用。了解手术在转移性脑病变患者中的作用和适应症对于有效管理这一不断增长的患者群体至关重要。

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