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序贯同步双侧全膝关节置换术的安全性与有效性:一项单中心回顾性队列研究。

Safety and efficacy of sequential simultaneous bilateral total knee arthroplasty: A single centre retrospective cohort study.

作者信息

Agarwala Sanjay, Menon Aditya

机构信息

Head- Orthopedics and Traumatology, Professional Services, P D Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim (West), Mumbai, 400016, Maharashtra, India.

Department of Orthopedics, DNB Orthopedics, P D Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim (West), Mumbai, 400016, India.

出版信息

J Clin Orthop Trauma. 2020 Jul;11(Suppl 4):S636-S644. doi: 10.1016/j.jcot.2020.05.015. Epub 2020 May 18.

Abstract

BACKGROUND

Simultaneous bilateral total knee arthroplasty (TKA) is a promising option for patients with bilateral arthritis of the knee because of the requirement of a single hospitalization and anesthetic regimen, reduced overall hospital stay, lower overall costs, and quicker recovery compared to staged bilateral TKA. However, there are conflicting reports on the safety of the procedure, with little data available in the Indian setting. Herein, we compared the efficacy and safety of sequential simultaneous bilateral TKA (SSBTKA) with those of unilateral TKA (UTKA).

METHODS

This retrospective analysis included cases of SSBTKA (n = 380, 760 knees) and UTKA (n = 754) performed by the same surgeon and followed up for a minimum duration of 1 year. The functional outcomes (postoperative changes in Oxford Knee Score [OKS] and Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC]), length of hospital stay (LOS), complications, and rates of revision and mortality were compared between the two groups.

RESULTS

The mean follow-up durations were 40.59 and 36.69 months for the UTKA and SSBTKA groups, respectively. The LOS was significantly longer in the SSBTKA group than in the UTKA group (Median [Interquartile range]: 4[1] vs. 3[0], p < 0.001). The OKS and WOMAC scores increased with time in both groups. The improvements in each of these scores at 3, 6, and 12 months postoperatively were either statistically similar between the two groups or, if statistically different, the differences were too small to be clinically meaningful. Blood transfusions (4% [SSBTKA] vs.0.3% [UTKA], p < 0.001), cardiac complications (1.6% vs. 0.4%, p = 0.034), urine retention (3.7% vs. 1.2%, p = 0.005), and deep infection (0.8% vs. 0%, p = 0.015) were significantly more frequent in the SSBTKA group. None of the patients in the UTKA group had to undergo revision surgery, whereas in the SSBTKA group, 2 (0.6%) patients underwent revision TKA. The overall mortality rates were low in both groups (0.8% [SSBTKA] and 0.3% [UTKA]), with no significant between-group difference (p = 0.209).

CONCLUSION

The functional outcomes and mortality rates associated with SSBTKA are comparable to those associated with UTKA. The risk of complications and the need for revision, although higher with SSBTKA, the actual numbers are low enough to justify its use. Although the LOS in SSBTKA is longer than that in UTKA, it is likely to be shorter than the cumulative LOS for two UTKA procedures (i.e. a staged bilateral TKA). Thus, SSBTKA appears to be a safe and effective choice for appropriately selected patients.

摘要

背景

同期双侧全膝关节置换术(TKA)对于双膝关节炎患者来说是一个有前景的选择,因为与分期双侧TKA相比,它只需一次住院和麻醉方案,能缩短整体住院时间,降低总体费用,并加快康复。然而,关于该手术安全性的报道存在矛盾,在印度环境下可用数据很少。在此,我们比较了序贯同期双侧TKA(SSBTKA)与单侧TKA(UTKA)的疗效和安全性。

方法

这项回顾性分析纳入了由同一位外科医生进行的SSBTKA(n = 380,760膝)和UTKA(n = 754)病例,并进行了至少1年的随访。比较了两组的功能结局(牛津膝关节评分[OKS]和西安大略和麦克马斯特大学骨关节炎指数[WOMAC]的术后变化)、住院时间(LOS)、并发症以及翻修率和死亡率。

结果

UTKA组和SSBTKA组的平均随访时间分别为40.59个月和36.69个月。SSBTKA组的LOS显著长于UTKA组(中位数[四分位间距]:4[1]对3[0],p < 0.001)。两组的OKS和WOMAC评分均随时间增加。术后3、6和12个月时,两组中这些评分的改善在统计学上要么相似,要么即使有统计学差异,差异也小到没有临床意义。SSBTKA组的输血率(4%对0.3%[UTKA],p < 0.001)、心脏并发症(1.6%对0.4%,p = 0.034)、尿潴留(3.7%对1.2%,p = 0.005)和深部感染(0.8%对0%,p = 0.015)明显更频繁。UTKA组没有患者需要进行翻修手术,而SSBTKA组有2例(0.6%)患者接受了翻修TKA。两组的总体死亡率都很低(SSBTKA组为0.8%,UTKA组为0.3%),组间无显著差异(p = 0.209)。

结论

与SSBTKA相关的功能结局和死亡率与UTKA相当。SSBTKA的并发症风险和翻修需求虽然更高,但实际数字低到足以证明其使用的合理性。虽然SSBTKA的LOS比UTKA长,但可能比两次UTKA手术(即分期双侧TKA)的累计LOS短。因此,对于适当选择的患者,SSBTKA似乎是一种安全有效的选择。

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