Cunneen Colla, Kelly Michael, Nason Gregory, Ryan Eanna, Creavin Ben, Winter Des
Centre for Colorectal Disease, Department of Colorectal Surgery, St. Vincent's University Hospital, Dublin.
Department of Urology, Mater University Hospital, Dublin, Ireland.
Curr Urol. 2020 Jun;14(2):57-65. doi: 10.1159/000499258. Epub 2020 Jun 23.
Pelvic exenterative surgery is both complex and challenging, especially in the setting of locally recurrent disease. In recent decades, improved surgical techniques have facilitated more extensive resection of both locally advanced and recurrent pelvic malignancies, but its role in urological cancer surgery is highly selective. However, it remains an important part of the armamentarium for the management of bladder and prostate cancer cases where there is local invasion into adjacent organs or localized recurrence. Better diagnostics, reconstructive options and centralized care have reduced associated morbidity considerably, and it is still used rarely in palliative settings. Despite this, there is sparse prospective evidence reporting on long-term oncological or quality of life outcomes.
盆腔脏器清除术既复杂又具有挑战性,尤其是在局部复发性疾病的情况下。近几十年来,改进的手术技术有助于更广泛地切除局部晚期和复发性盆腔恶性肿瘤,但其在泌尿外科癌症手术中的作用具有高度选择性。然而,对于膀胱和前列腺癌局部侵犯相邻器官或局部复发的病例,它仍然是治疗手段中的重要组成部分。更好的诊断、重建选择和集中护理已大幅降低了相关发病率,并且在姑息治疗环境中仍很少使用。尽管如此,关于长期肿瘤学或生活质量结果的前瞻性证据却很少。