原发性血小板增多症患者的血小板单采术：一例报告
Thrombocytapheresis in Patient with Essential Thrombocythemia: A Case Report.
作者信息
Elhassan Afra M, Alsaud Arwa, Yassin Mohamed A, Aldapt Mahmood, Riaz Lubna, Ghori Firdous, Bin Ahmad Aiman, Abdulla Mohammad
机构信息
Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.
National Centre for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar.
出版信息
Case Rep Oncol. 2020 Jun 16;13(2):675-679. doi: 10.1159/000507651. eCollection 2020 May-Aug.
Essential thrombocythemia (ET) is one of the myeloproliferative neoplasms, characterized by persistent thrombocytosis, platelets >450,000/μL, and evident clonal abnormalities like JAK2 V617F, MPL, CALR mutation and not fulfilling WHO criteria for MDS, CML, PV, and IDA. Here we report a 24-year-old female who presented with headache and was found to have thrombocytosis with a platelet count of 2,141 × 10/μL, diagnosed as ET as per WHO criteria 2008; she required ICU admission and thrombocytapheresis with a favorable outcome.
原发性血小板增多症（ET）是一种骨髓增殖性肿瘤，其特征为持续性血小板增多，血小板计数>450,000/μL，且存在明显的克隆性异常，如JAK2 V617F、MPL、CALR突变，且不符合世界卫生组织（WHO）关于骨髓增生异常综合征（MDS）、慢性粒细胞白血病（CML）、真性红细胞增多症（PV）和缺铁性贫血（IDA）的诊断标准。在此，我们报告一名24岁女性，因头痛就诊，发现血小板增多，血小板计数为2,141×10/μL，根据2008年WHO标准诊断为ET；她需要入住重症监护病房（ICU）并进行血小板单采术，结果良好。
Zotero 插件