Chaudhury Abhijit, Parija Subhash Chandra
Department of Microbiology, Sri Venkateswara Institute of Medical Sciences and Sri Padmavathi Medical College (Women), Tirupati, Andhra Pradesh, India.
Vice-Chancellor, Sri Balaji Vidyapeeth, Puducherry, India.
Trop Parasitol. 2020 Jan-Jun;10(1):7-11. doi: 10.4103/tp.TP_81_19. Epub 2020 May 20.
is a flagellate protozoan parasite which was originally described as a commensal in the gut of cockroaches. From the 1990s, reports started coming out of peoples Republic of China about its possible role in bronchopulmonary infections, and this was followed by reports from some other parts of the world as well. There had been some skepticism regarding the misidentification of bronchial ciliated epithelial cells as , but recent use of molecular diagnosis has come as an aid in clearing the controversy. This review focuses on the various aspects of the parasite including its biology, epidemiology, clinical manifestations, laboratory diagnosis, and the treatment aspects. Molecular diagnosis has recently been employed and more reports concerning its validation is needed. More basic research concerning the genomic and proteomic analysis is necessary to develop reliable molecular and serological tests for this parasite in future.
是一种鞭毛虫原生动物寄生虫,最初被描述为蟑螂肠道中的共生体。从20世纪90年代开始,中华人民共和国有报道称其可能在支气管肺部感染中起作用,随后世界其他一些地区也有相关报道。曾有人对将支气管纤毛上皮细胞误鉴定为存在怀疑,但最近分子诊断的应用有助于消除这一争议。本综述重点关注该寄生虫的各个方面,包括其生物学、流行病学、临床表现、实验室诊断和治疗方面。最近已采用分子诊断,还需要更多关于其验证的报告。未来有必要开展更多关于基因组和蛋白质组分析的基础研究,以开发针对该寄生虫的可靠分子和血清学检测方法。