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持续性肉芽肿患者支气管肺毛滴虫病的诊断与治疗:一例报告

Diagnosis and Treatment of Bronchopulmonary Lophomoniasis in a Patient with Persistent Granuloma: A Case Report.

作者信息

Mier-Briseño Antonio, Ramírez-Alanís Eloísa, Benavides-Huerto Miguel Armando, Lagunas-Rangel Francisco Alejandro

机构信息

Department of Pneumology, Morelia Medical Clinic, Morelia 58260, Michoacán, Mexico.

Clinical Analisys Laboratory, Sanatorio La Luz, Morelia 58260, Michoacán, Mexico.

出版信息

Reports (MDPI). 2024 Nov 19;7(4):102. doi: 10.3390/reports7040102.

DOI:10.3390/reports7040102
PMID:40757707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12199965/
Abstract

: is a multiflagellate anaerobic protozoan that usually inhabits the intestines of insects, mainly cockroaches. However, bronchopulmonary infections caused by this parasite have been increasingly reported worldwide in recent decades. We provide important information for the diagnosis of this disease, which often goes undetected and frequently leads to misdiagnosis and inadequate treatment. It is noteworthy that this is the third case reported in Mexico. : A 37-year-old male patient was hospitalized several times for pneumonia with a persistent granuloma in the right bronchial lobe. After extensive testing, the patient was diagnosed with bronchopulmonary lophomoniasis and successfully treated with metronidazole. : Clinicians worldwide should be aware of the existence of lophomoniasis, especially in low-income regions with poor sanitation and high insect exposure. This parasitic infection, although rare, may be underestimated due to its nonspecific respiratory symptoms, which may mimic other infections.

摘要

是一种多鞭毛厌氧原生动物,通常栖息在昆虫肠道内,主要是蟑螂。然而,近几十年来,全球范围内由这种寄生虫引起的支气管肺部感染报告日益增多。我们为这种常未被发现且常导致误诊和治疗不足的疾病的诊断提供了重要信息。值得注意的是,这是墨西哥报告的第三例病例。一名37岁男性患者因右支气管叶持续性肉芽肿性肺炎多次住院。经过广泛检查,该患者被诊断为支气管肺部洛蒙虫病,并成功接受甲硝唑治疗。全球临床医生应意识到洛蒙虫病的存在,尤其是在卫生条件差和昆虫接触率高的低收入地区。这种寄生虫感染虽然罕见,但由于其非特异性呼吸道症状可能与其他感染相似,可能被低估。

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本文引用的文献

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Coinfection of pulmonary lophomoniasis, tuberculosis, and hydatid cyst in a pediatric autism patient: a case report and literature review.儿童自闭症患者肺部组织胞浆菌病、肺结核和包虫囊肿合并感染:病例报告及文献复习。
BMC Pediatr. 2024 Oct 30;24(1):689. doi: 10.1186/s12887-024-05180-5.
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The co-infection of pulmonary hydatid cyst, lophomoniasis and tuberculosis in a patient with resistant respiratory symptoms; a case report study.患者出现耐药性呼吸道症状,合并肺包虫囊肿、肺匐行疹和肺结核感染;病例报告研究。
BMC Infect Dis. 2024 Jan 2;24(1):11. doi: 10.1186/s12879-023-08907-4.
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First Molecular Evidence of Emerging Lophomonas Pathogen Among Patients Suspected of Having Pulmonary Tuberculosis in Mazandaran Province, Northern Iran.
伊朗北部马赞达兰省疑似肺结核患者中新兴唇滴虫病原体的首次分子证据。
Acta Parasitol. 2024 Mar;69(1):1041-1045. doi: 10.1007/s11686-023-00729-3. Epub 2023 Dec 18.
4
as a respiratory pathogen-jumping the gun.作为一种呼吸道病原体——操之过急。
J Clin Microbiol. 2024 Jan 17;62(1):e0084523. doi: 10.1128/jcm.00845-23. Epub 2023 Oct 30.
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A co-infection of Pneumocystis jirovecii and Lophomonas blattarum causing pneumonia in a patient with adenocarcinoma of lung.耶氏肺孢子菌和蜚蠊滴虫合并感染导致一名肺癌腺癌患者发生肺炎。
Indian J Med Microbiol. 2023 Jan-Feb;41:25-27. doi: 10.1016/j.ijmmb.2022.12.003. Epub 2022 Dec 23.
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High Occurrence of Emerged Infection among Patients Suspected of Having Pulmonary Tuberculosis: In-House PCR-Based Evidence.疑似肺结核患者中新发感染的高发生率:基于院内聚合酶链反应的证据
Interdiscip Perspect Infect Dis. 2022 Dec 1;2022:2742164. doi: 10.1155/2022/2742164. eCollection 2022.
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Effective Treatment of Chronic Cough with Tinidazole as the Newest Antiprotozoa against .以替硝唑作为最新抗原生动物药物对慢性咳嗽进行有效治疗 。 不过你提供的原文似乎不太完整,“against”后面缺少具体内容。
J Parasitol Res. 2022 Nov 3;2022:2413941. doi: 10.1155/2022/2413941. eCollection 2022.
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and co-infection: the first molecular evidence to overcome potential diagnostic pitfalls.以及合并感染:克服潜在诊断陷阱的首个分子证据。
Oxf Med Case Reports. 2022 Jul 26;2022(7):omac064. doi: 10.1093/omcr/omac064. eCollection 2022 Jul.
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Acta Parasitol. 2022 Mar;67(1):535-538. doi: 10.1007/s11686-021-00468-3. Epub 2021 Oct 22.