Sharma Sonam, Dawson Leelavathi
Department of Pathology, Kalpana Chawla Government Medical College, Karnal, Haryana, India.
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Trop Parasitol. 2020 Jan-Jun;10(1):50-55. doi: 10.4103/tp.TP_44_19. Epub 2020 May 20.
Hemophagocytic lymphohistiocytosis (HLH) is an unusual multifaceted clinicopathological entity that often remains misdiagnosed and can be fatal if not timely detected or treated. It can be familial or associated with different types of infections, autoimmune disorders, and malignancies. Parasitic infection-associated HLH has been rarely documented in the literature with only a handful of them being reported due to infection. We describe an extremely rare case of pancytopenia induced by HLH resulting from infection in a 7-year-old girl, which posed as a diagnostic challenge and led to a therapeutic delay.
噬血细胞性淋巴组织细胞增生症(HLH)是一种不常见的多方面的临床病理实体,常常被误诊,如果不及时发现或治疗可能会致命。它可以是家族性的,也可与不同类型的感染、自身免疫性疾病及恶性肿瘤相关。寄生虫感染相关的HLH在文献中鲜有记载,仅有少数病例因感染而被报道。我们描述了一名7岁女孩因 感染导致HLH引起全血细胞减少的极其罕见病例,这构成了诊断挑战并导致治疗延误。