Research Center for Advanced Technologies in Cardiovascular Medicine, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, UK.
J Immunol Res. 2020 Jul 25;2020:5193036. doi: 10.1155/2020/5193036. eCollection 2020.
Coronary artery diseases (CAD), as a leading cause of mortality around the world, has attracted the researchers' attention for years to find out its underlying mechanisms and causes. Among the various key players in the pathogenesis of CAD cytokines, microRNAs (miRNAs) are crucial. In this study, besides providing a comprehensive overview of the involvement of cytokines, growth factors, and miRNAs in CAD, the interplay between miRNA with cytokine or growth factors during the development of CAD is discussed.
冠心病（CAD）作为全球主要的致死原因之一，多年来一直吸引着研究人员的关注，旨在探究其潜在的发病机制和病因。在 CAD 发病机制中的众多关键因子中，细胞因子和 microRNAs（miRNAs）至关重要。本研究除了全面概述细胞因子、生长因子和 miRNAs 在 CAD 中的作用外，还探讨了 miRNA 与细胞因子或生长因子在 CAD 发展过程中的相互作用。
