Chronic Traumatic Encephalopathy Center, Boston University School of Medicine, Boston, Massachusetts.
Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, Nevada.
Semin Neurol. 2020 Aug;40(4):353-358. doi: 10.1055/s-0040-1713622. Epub 2020 Aug 10.
The long-term effects of repetitive head impacts have been recognized for close to a century. What is now referred to as chronic traumatic encephalopathy (CTE) was first described by Martland in 1928 in a series of boxers. Over the years, several important articles were published, including Critchley's 1957 report where he introduced the term "chronic traumatic encephalopathy," Robert's study in 1969 which provided evidence of the prevalence of neurological impairment in retired fighters, and Corsellis' initial description of the pathology of CTE. However, what brought public attention to the issue of CTE in sports were the postmortem findings of CTE pathology in professional American football players, initially reported by Omalu and subsequently in a large series by McKee. There is now standardization of pathological criteria for CTE and recognition that it can be seen across all activities that involve repetitive head impacts.
重复性头部撞击的长期影响已经被认识近一个世纪了。现在被称为慢性创伤性脑病(CTE)的疾病最早是由 Martland 在 1928 年描述的一系列拳击手中发现的。多年来,发表了几篇重要的文章,包括 Critchley 在 1957 年的报告,他引入了“慢性创伤性脑病”一词,Robert 在 1969 年的研究提供了退役拳手神经损伤普遍存在的证据,以及 Corsellis 对 CTE 病理学的初步描述。然而,引起公众对运动中 CTE 问题关注的是职业美式足球运动员尸检中发现的 CTE 病理学,最初由 Omalu 报道,随后 McKee 进行了大量的系列报道。现在已经有了 CTE 的病理标准,并认识到它可以在所有涉及重复性头部撞击的活动中看到。