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1
Cloning of the recB, recC, and recD genes from Proteus mirabilis in Escherichia coli: in vivo formation of active hybrid enzymes.奇异变形杆菌recB、recC和recD基因在大肠杆菌中的克隆：活性杂交酶的体内形成
J Bacteriol. 1988 Mar;170(3):1412-4. doi: 10.1128/jb.170.3.1412-1414.1988.
2
The recA-recBCD dependent recombination pathways of Serratia marcescens and Proteus mirabilis in Escherichia coli: functions of hybrid enzymes and hybrid pathways.粘质沙雷氏菌和奇异变形杆菌在大肠杆菌中的recA-recBCD依赖性重组途径：杂合酶和杂合途径的功能。
Biochimie. 1991 Apr;73(4):375-84. doi: 10.1016/0300-9084(91)90104-9.
3
recD: the gene for an essential third subunit of exonuclease V.
Proc Natl Acad Sci U S A. 1986 Aug;83(15):5558-62. doi: 10.1073/pnas.83.15.5558.
4
Functional analyses of Proteus mirabilis wild-type and mutant RecBCD enzymes in Escherichia coli reveal a new mutant phenotype.
Mol Microbiol. 1989 Dec;3(12):1777-84. doi: 10.1111/j.1365-2958.1989.tb00163.x.
5
Recombination and UV resistance of Escherichia coli with the cloned recA and recBCD genes of Serratia marcescens and Proteus mirabilis: evidence for an advantage of intraspecies combination of P. mirabilis RecA protein and RecBCD enzyme.携带粘质沙雷氏菌和奇异变形杆菌克隆的recA和recBCD基因的大肠杆菌的重组与紫外线抗性：奇异变形杆菌RecA蛋白和RecBCD酶种内组合具有优势的证据
J Gen Microbiol. 1992 Jan;138(1):31-8. doi: 10.1099/00221287-138-1-31.
6
The recombination hot spot chi activates RecBCD recombination by converting Escherichia coli to a recD mutant phenocopy.重组热点chi通过将大肠杆菌转变为recD突变体表型模拟物来激活RecBCD重组。
Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6244-8. doi: 10.1073/pnas.92.14.6244.
7
All three subunits of RecBCD enzyme are essential for DNA repair and low-temperature growth in the Antarctic Pseudomonas syringae Lz4W.RecBCD 酶的三个亚基对于南极假单胞菌 Lz4W 的 DNA 修复和低温生长都是必需的。
PLoS One. 2010 Feb 25;5(2):e9412. doi: 10.1371/journal.pone.0009412.
8
The genetic dependence of recombination in recD mutants of Escherichia coli.大肠杆菌recD突变体中重组的遗传依赖性。
Genetics. 1988 Sep;120(1):37-45. doi: 10.1093/genetics/120.1.37.
9
Chi and the RecBC D enzyme of Escherichia coli.大肠杆菌的Chi序列与RecBC D酶
Annu Rev Genet. 1994;28:49-70. doi: 10.1146/annurev.ge.28.120194.000405.
10
Bacteriophage P22 Abc2 protein binds to RecC increases the 5' strand nicking activity of RecBCD and together with lambda bet, promotes Chi-independent recombination.噬菌体P22 Abc2蛋白与RecC结合，增强RecBCD的5'链切口活性，并与λ bet一起促进不依赖于Chi序列的重组。
J Mol Biol. 2000 Feb 18;296(2):385-401. doi: 10.1006/jmbi.1999.3486.

引用本文的文献

1
Biochemistry of homologous recombination in Escherichia coli.大肠杆菌中同源重组的生物化学
Microbiol Rev. 1994 Sep;58(3):401-65. doi: 10.1128/mr.58.3.401-465.1994.
2
Evidence that recBC-dependent degradation of duplex DNA in Escherichia coli recD mutants involves DNA unwinding.大肠杆菌recD突变体中recBC依赖的双链DNA降解涉及DNA解旋的证据。
J Bacteriol. 1992 Aug;174(16):5424-9. doi: 10.1128/jb.174.16.5424-5429.1992.
3
Inhibition of the recBCD-dependent activation of Chi recombinational hot spots in SOS-induced cells of Escherichia coli.在大肠杆菌SOS诱导细胞中对recBCD依赖性Chi重组热点激活的抑制作用。
J Bacteriol. 1992 Feb;174(4):1172-8. doi: 10.1128/jb.174.4.1172-1178.1992.

本文引用的文献

1
Interspecies recA protein substitution in Escherichia coli and Proteus mirabilis.大肠杆菌和奇异变形杆菌中的种间RecA蛋白替代
Mol Gen Genet. 1982;185(3):481-6. doi: 10.1007/BF00334144.
2
Identification of the Escherichia coli recB and recC gene products.大肠杆菌recB和recC基因产物的鉴定。
Nature. 1981 Dec 10;294(5841):578-80. doi: 10.1038/294578a0.
3
Escherichia coli recBC deletion mutants.大肠杆菌recBC缺失突变体
J Bacteriol. 1984 Nov;160(2):788-91. doi: 10.1128/jb.160.2.788-791.1984.
4
Physical and biochemical analysis of the cloned recB and recC genes of Escherichia coli K-12.大肠杆菌K-12克隆的recB和recC基因的物理及生化分析
J Bacteriol. 1984 Jan;157(1):21-7. doi: 10.1128/jb.157.1.21-27.1984.
5
Fine structure of the recB and recC gene region of Escherichia coli.大肠杆菌recB和recC基因区域的精细结构
Biochem Biophys Res Commun. 1982 Nov 30;109(2):414-22. doi: 10.1016/0006-291x(82)91737-5.
6
Unwinding and rewinding of DNA by the RecBC enzyme.RecBC酶对DNA的解旋和重新缠绕。
Cell. 1980 Nov;22(2 Pt 2):447-57. doi: 10.1016/0092-8674(80)90355-4.
7
UV-induced allevation of lambda restriction in Escherichia coli K-12: kinetics of induction and specificity of this SOS function.紫外线诱导减轻大肠杆菌K-12中的λ限制：此SOS功能的诱导动力学和特异性
Mol Gen Genet. 1982;186(1):111-7. doi: 10.1007/BF00422921.
8
Genetic control of damage-inducible restriction alleviation in Escherichia coli K12: an SOS function not repressed by lexA.大肠杆菌K12中损伤诱导性限制缓解的遗传控制：一种不受lexA抑制的SOS功能。
Mol Gen Genet. 1984;197(2):297-303. doi: 10.1007/BF00330977.
9
Cloning and characterization of recA genes froM Proteus vulgaris, Erwinia carotovora, Shigella flexneri, and Escherichia coli B/r.普通变形杆菌、胡萝卜软腐欧文氏菌、福氏志贺氏菌和大肠杆菌B/r中recA基因的克隆与特性分析
J Bacteriol. 1984 Oct;160(1):153-60. doi: 10.1128/jb.160.1.153-160.1984.
10
The mechanism of degradation of duplex deoxyribonucleic acid by the recBC enzyme of Escherichia coli K-12.大肠杆菌K-12的recBC酶降解双链脱氧核糖核酸的机制。
J Biol Chem. 1974 Jul 10;249(13):4286-94.

奇异变形杆菌recB、recC和recD基因在大肠杆菌中的克隆：活性杂交酶的体内形成

Cloning of the recB, recC, and recD genes from Proteus mirabilis in Escherichia coli: in vivo formation of active hybrid enzymes.

作者信息

Weichenhan D, Wackernagel W

机构信息

Fachbereich Biologie, Universität Oldenburg, Federal Republic of Germany.

出版信息

J Bacteriol. 1988 Mar;170(3):1412-4. doi: 10.1128/jb.170.3.1412-1414.1988.

DOI:10.1128/jb.170.3.1412-1414.1988
PMID:3277957
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC210929/
Abstract

We cloned chromosomal DNA fragments from Proteus mirabilis which complement recBCD deletion mutants of Escherichia coli by restoring (i) recombination proficiency in conjugation, (ii) normal resistance to UV irradiation, and (iii) ATP-dependent exonuclease activity for duplex DNA. The data indicate that the order of the genes thyA, recC, recB, recD, and argA is similar in both P. mirabilis and E. coli. Hybrid enzymes formed in vivo were active in repair and recombination.

摘要

我们从奇异变形杆菌中克隆了染色体DNA片段，这些片段通过恢复（i）接合中的重组能力、（ii）对紫外线照射的正常抗性以及（iii）双链DNA的ATP依赖性核酸外切酶活性，来互补大肠杆菌的recBCD缺失突变体。数据表明，thyA、recC、recB、recD和argA基因在奇异变形杆菌和大肠杆菌中的顺序相似。体内形成的杂合酶在修复和重组中具有活性。