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[核裂变放射性核素产物衰变对酿酒酵母细胞的遗传效应。掺入不同倍体细胞中的89Sr衰变的致死效应及放射敏感性]

[Genetic effects of the decay of radionuclide products of nuclear fission in Saccharomyces cerevisiae cells. Lethal effects of the decay of 89Sr incorporated in cells of different ploidies and radiosensitivity].

作者信息

Korolev V G, Gracheva L M

出版信息

Radiobiologiia. 1988 Jan-Feb;28(1):134-7.

PMID:3278334
Abstract

Decay of 89Sr incorporated in yeast cells produces a pronounced inactivating effect. The transmutation mainly contributes (about 80%) to cell inactivation. Haploid cells are more sensitive to 89Sr disintegration than diploid and tetraploid ones. A radiosensitive mutant XRS2, that is particularly sensitive to the transmutation effect of radionuclides, has proved to be sensitive to 89Sr transmutation as well. At the same time, another radiosensitive mutant, rad 54, does not virtually differ from the wild-type strain by its sensitivity to 89Sr decay.

摘要

掺入酵母细胞中的89Sr衰变产生明显的失活效应。嬗变对细胞失活的贡献主要(约80%)。单倍体细胞比二倍体和四倍体细胞对89Sr衰变更敏感。已证明对放射性核素嬗变效应特别敏感的辐射敏感突变体XRS2对89Sr嬗变也敏感。同时,另一个辐射敏感突变体rad 54在对89Sr衰变的敏感性方面与野生型菌株几乎没有差异。

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