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计算机断层扫描引导下微波消融治疗肺癌的疗效及并发症

The efficacy and complications of computed tomography guided microwave ablation in lung cancer.

作者信息

Chen Bin, Li Wei, Liu Yu, Ren Shengxiang, Wang Lei, Wang Hao, Zhao Sha, Ye Lingyun, He Yayi, Zhou Caicun

机构信息

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China; Tongji University, Shanghai, China.

出版信息

Ann Palliat Med. 2020 Sep;9(5):2760-2765. doi: 10.21037/apm-20-255. Epub 2020 Jul 30.

DOI:10.21037/apm-20-255
PMID:32787355
Abstract

BACKGROUND

This study aimed to explore the effect and safety of computed tomography (CT) guided microwave ablation for lung cancer.

METHODS

We retrospectively enrolled CT guided microwave ablation of lung cancer patients in Shanghai Pulmonary Hospital from March 2016 to September 2019. All patients were pathologically confirmed by fine needle biopsy before microwave ablation. We reviewed CT imaging of 45 patients with lung cancer before and after microwave ablation and recorded the complications. Date were analyzed by paired-samples T-test and one-way analysis of variance.

RESULTS

In 45 lung cancer patients received CT guided microwave ablation, the tumor diameter changed from 2.35±0.22 cm before surgery to 2.26±0.19 cm after surgery, average reduction by 0.09 cm (P=0.518). With microwave ablation treatment, the disease control rate reached 82.93%, and the incidence of pneumothorax was 13.3%, with no other related adverse. The successful rate of operation was 100%, and there was no severe or death related adverse.

CONCLUSIONS

CT-guided microwave ablation is an effective method in the treatment of lung cancer, with a low incidence of complications. It is a safe and effective method for the treatment of lung cancer.

摘要

背景

本研究旨在探讨计算机断层扫描(CT)引导下微波消融治疗肺癌的疗效和安全性。

方法

我们回顾性纳入了2016年3月至2019年9月在上海肺科医院接受CT引导下肺癌微波消融治疗的患者。所有患者在微波消融前均经细针穿刺活检病理确诊。我们回顾了45例肺癌患者微波消融前后的CT影像并记录并发症。数据采用配对样本T检验和单因素方差分析。

结果

45例接受CT引导下微波消融的肺癌患者,肿瘤直径从术前的2.35±0.22 cm变为术后的2.26±0.19 cm,平均缩小0.09 cm(P = 0.518)。经微波消融治疗,疾病控制率达82.93%,气胸发生率为13.3%,无其他相关不良反应。手术成功率为100%,无严重或致死性相关不良反应。

结论

CT引导下微波消融是治疗肺癌的有效方法,并发症发生率低。是一种安全有效的肺癌治疗方法。

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