Department of Oncology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Shandong Lung Cancer Institute, Jinan, China.
Department of Cardiology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Medicine and Health Key Laboratory of Cardiac Electrophysiology and Arrhythmia, Jinan, China.
Thorac Cancer. 2022 Sep;13(18):2557-2565. doi: 10.1111/1759-7714.14589. Epub 2022 Aug 1.
This retrospective study aimed to assess the safety and efficacy of microwave ablation for lung tumors adjacent to the interlobar fissures.
From May 2020 to April 2021, 59 patients with 66 lung tumors (mean diameter, 16.9 ± 7.7 mm; range, 6-30 mm) adjacent to the interlobar fissures who underwent microwave ablation at our institution were identified and included in this study. Based on the relationship between the tumor and the interlobar fissure, tumors can be categorized into close to the fissure, causing the fissure, and involving the fissure. The complete ablation rate, local progression-free survival, complications, and associated factors were analyzed.
All 66 histologically proven tumors were treated using computed tomography-guided microwave ablation. The complete ablation rate was 95.5%. Local progression-free survival at 3, 6, 9, and 12 months were 89.4%, 83.3%, 74.2%, and 63.6%, respectively. The complications included pneumothorax (34.8%), pleural effusion (24.2%), cavity (18.2%), and pulmonary infection (7.6%). There were statistical differences in the incidence of pneumothorax, cavity, and delayed complications between the groups with and without antenna punctures through the fissure.
Microwave ablation is a safe and effective treatment for lung tumor adjacent to the interlobar fissure. Antenna puncturing though the interlobar fissure may be a potential risk factor for pneumothorax, cavity, and delayed complications.
本回顾性研究旨在评估微波消融治疗毗邻叶间裂的肺部肿瘤的安全性和有效性。
2020 年 5 月至 2021 年 4 月，我们机构对 59 例 66 个毗邻叶间裂的肺部肿瘤（平均直径 16.9±7.7mm；范围 6-30mm）患者进行了微波消融治疗，这些患者被纳入本研究。根据肿瘤与叶间裂的关系，肿瘤可分为靠近叶间裂、引起叶间裂、累及叶间裂。分析完全消融率、局部无进展生存率、并发症及相关因素。
所有 66 个经组织学证实的肿瘤均采用 CT 引导下微波消融治疗。完全消融率为 95.5%。3、6、9 和 12 个月的局部无进展生存率分别为 89.4%、83.3%、74.2%和 63.6%。并发症包括气胸（34.8%）、胸腔积液（24.2%）、空洞（18.2%）和肺部感染（7.6%）。有天线经叶间裂穿刺与无天线经叶间裂穿刺两组患者气胸、空洞和迟发性并发症的发生率存在统计学差异。
微波消融治疗毗邻叶间裂的肺部肿瘤是一种安全有效的治疗方法。天线经叶间裂穿刺可能是气胸、空洞和迟发性并发症的潜在危险因素。
