University of Khartoum, Khartoum, Sudan.
Hamad Medical Corporation, Doha, Qatar.
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620949309. doi: 10.1177/2324709620949309.
Cerebral venous sinus thrombosis (CVT) is an uncommon yet serious condition. While CVT has many known precipitants and etiologies, hyperthyroidism as a precipitant of CVT is not well understood. This study reported a case of a 41-year-old male with a 4-year history of hyperthyroidism presented with seizure. Consequently, a diagnosis of superior sagittal sinus thrombosis was confirmed by computed tomography and magnetic resonance (MR) venograms. Extensive investigations yielded no apparent underlying cause, but laboratory findings were consistent with uncontrolled hyperthyroidism. The patient improved rapidly following anticoagulation. Follow-up MR and MRV scans 2 months after treatment revealed full recanalization of the superior sagittal sinus. This case report highlighted hyperthyroidism, as a procoagulant condition, resulting specifically in superior sagittal sinus thrombosis.
脑静脉窦血栓形成(CVT)是一种不常见但严重的疾病。虽然 CVT 有许多已知的诱因和病因,但甲状腺功能亢进症作为 CVT 的诱因尚未得到很好的理解。本研究报告了一例 41 岁男性,有 4 年甲状腺功能亢进症病史,表现为癫痫发作。因此,通过计算机断层扫描和磁共振(MR)静脉造影证实了上矢状窦血栓形成的诊断。广泛的检查未发现明显的潜在原因,但实验室检查结果与未控制的甲状腺功能亢进症一致。抗凝治疗后,患者迅速好转。治疗 2 个月后的随访 MR 和 MRV 扫描显示上矢状窦完全再通。本病例报告强调了甲状腺功能亢进症作为一种促凝状态,特别是导致上矢状窦血栓形成。