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1
Alternative splicing of leptin receptor overlapping transcript in osteosarcoma.骨肉瘤中瘦素受体重叠转录本的可变剪接
Exp Biol Med (Maywood). 2020 Oct;245(16):1437-1443. doi: 10.1177/1535370220949139. Epub 2020 Aug 12.
2
Whole transcriptome analysis identifies differentially regulated networks between osteosarcoma and normal bone samples.全转录组分析确定了骨肉瘤与正常骨样本之间差异调节的网络。
Exp Biol Med (Maywood). 2017 Dec;242(18):1802-1811. doi: 10.1177/1535370217736512. Epub 2017 Oct 19.
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RNA Sequencing of Osteosarcoma Gene Expression Profile Revealed that miR-214-3p Facilitates Osteosarcoma Cell Proliferation via Targeting Ubiquinol-Cytochrome c Reductase Core Protein 1 (UQCRC1).骨肉瘤基因表达谱的 RNA 测序显示，miR-214-3p 通过靶向泛醌细胞色素 c 还原酶核心蛋白 1（UQCRC1）促进骨肉瘤细胞增殖。
Med Sci Monit. 2019 Jul 5;25:4982-4991. doi: 10.12659/MSM.917375.
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Extracellular Vesicle RNA Sequencing Reveals Dramatic Transcriptomic Alterations Between Metastatic and Primary Osteosarcoma in a Liquid Biopsy Approach.外泌体 RNA 测序揭示了液体活检方法中转移性和原发性骨肉瘤之间戏剧性的转录组改变。
Ann Surg Oncol. 2018 Sep;25(9):2642-2651. doi: 10.1245/s10434-018-6642-z. Epub 2018 Jul 6.
5
Genomic characterization and tissue distribution of leptin receptor and leptin receptor overlapping transcript genes in the pufferfish, Takifugu rubripes.红鳍东方鲀中瘦素受体及瘦素受体重叠转录本基因的基因组特征与组织分布
Gen Comp Endocrinol. 2008 Aug;158(1):108-14. doi: 10.1016/j.ygcen.2008.06.003. Epub 2008 Jun 8.
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Analyzing the Interactions of mRNAs and ncRNAs to Predict Competing Endogenous RNA Networks in Osteosarcoma Chemo-Resistance.分析 mRNAs 和 ncRNAs 的相互作用，预测骨肉瘤化疗耐药中的竞争内源性 RNA 网络。
Mol Ther. 2019 Mar 6;27(3):518-530. doi: 10.1016/j.ymthe.2019.01.001. Epub 2019 Jan 7.
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Altered expression and deletion of RMO1 in osteosarcoma.骨肉瘤中RMO1的表达改变与缺失
Int J Cancer. 2005 May 1;114(5):738-46. doi: 10.1002/ijc.20786.
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Identification of chromosomal aberrations associated with disease progression and a novel 3q13.31 deletion involving LSAMP gene in osteosarcoma.骨肉瘤中与疾病进展相关的染色体畸变鉴定及涉及LSAMP基因的新型3q13.31缺失
Int J Oncol. 2009 Oct;35(4):775-88. doi: 10.3892/ijo_00000390.
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Identification of differentially expressed genes in the development of osteosarcoma using RNA-seq.利用RNA测序技术鉴定骨肉瘤发展过程中的差异表达基因。
Oncotarget. 2016 Dec 27;7(52):87194-87205. doi: 10.18632/oncotarget.13554.
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Leptin receptor overlapping transcript (LepROT) gene participates in insulin pathway through FoxO.瘦素受体重叠转录本（LepROT）基因通过叉头框蛋白O（FoxO）参与胰岛素信号通路。
Gene. 2016 Aug 1;587(1):64-9. doi: 10.1016/j.gene.2016.04.036. Epub 2016 Apr 20.
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Preptin: A New Bone Metabolic Parameter?前动力蛋白：一种新的骨代谢参数？
Metabolites. 2023 Sep 4;13(9):991. doi: 10.3390/metabo13090991.
2
The splicing factor proline and glutamine rich promotes the growth of osteosarcoma via the c-Myc signaling pathway.富含脯氨酸和谷氨酰胺的剪接因子通过c-Myc信号通路促进骨肉瘤生长。
Am J Cancer Res. 2023 Jun 15;13(6):2488-2503. eCollection 2023.
3
Functional role of MicroRNA/PI3K/AKT axis in osteosarcoma.微小RNA/PI3K/AKT轴在骨肉瘤中的功能作用
Front Oncol. 2023 Jun 19;13:1219211. doi: 10.3389/fonc.2023.1219211. eCollection 2023.
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Genome-wide identification of alternative splicing and splicing regulated in immune infiltration in osteosarcoma patients.骨肉瘤患者免疫浸润中可变剪接及剪接受调控的全基因组鉴定。
Front Genet. 2023 Apr 17;14:1051192. doi: 10.3389/fgene.2023.1051192. eCollection 2023.
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Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma.骨肉瘤的缺氧-免疫相关微环境预后标志物
Front Cell Dev Biol. 2022 Dec 12;10:974851. doi: 10.3389/fcell.2022.974851. eCollection 2022.
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Osteosarcoma subtypes based on platelet-related genes and tumor microenvironment characteristics.基于血小板相关基因和肿瘤微环境特征的骨肉瘤亚型
Front Oncol. 2022 Sep 23;12:941724. doi: 10.3389/fonc.2022.941724. eCollection 2022.
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Innovative approaches for treatment of osteosarcoma.创新性骨肉瘤治疗方法。
Exp Biol Med (Maywood). 2022 Feb;247(4):310-316. doi: 10.1177/15353702211067718. Epub 2022 Jan 19.
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Leptin Receptor Overlapping Transcript (LEPROT) Is Associated with the Tumor Microenvironment and a Prognostic Predictor in Pan-Cancer.瘦素受体重叠转录本（LEPROT）与肿瘤微环境相关，是泛癌的一种预后预测指标。
Front Genet. 2021 Nov 11;12:749435. doi: 10.3389/fgene.2021.749435. eCollection 2021.
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A Novel Overall Survival Prediction Signature Based on Cancer Stem Cell-Related Genes in Osteosarcoma.一种基于骨肉瘤中癌症干细胞相关基因的新型总生存预测特征
Front Cell Dev Biol. 2021 Oct 18;9:753414. doi: 10.3389/fcell.2021.753414. eCollection 2021.
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Upregulation of 15 Antisense Long Non-Coding RNAs in Osteosarcoma.骨肉瘤中 15 种反义长非编码 RNA 的上调。
Genes (Basel). 2021 Jul 26;12(8):1132. doi: 10.3390/genes12081132.
本文引用的文献
1
Survival of osteosarcoma patients following diagnosis of synchronous skip metastases.骨肉瘤患者诊断为同步跳跃转移后的生存率。
J Orthop. 2019 Oct 24;18:121-125. doi: 10.1016/j.jor.2019.10.003. eCollection 2020 Mar-Apr.
2
IL-6 Promotes Cancer Stemness and Oncogenicity in U2OS and MG-63 Osteosarcoma Cells by Upregulating the OPN-STAT3 Pathway.白细胞介素-6通过上调骨桥蛋白-信号转导子和转录激活子3通路促进U2OS和MG-63骨肉瘤细胞的癌干性和致癌性。
J Cancer. 2019 Oct 21;10(26):6511-6525. doi: 10.7150/jca.29931. eCollection 2019.
3
Significance of alternative splicing in cancer cells.剪接变异在癌细胞中的意义。
Chin Med J (Engl). 2020 Jan 20;133(2):221-228. doi: 10.1097/CM9.0000000000000542.
4
Early Diagnosis: A Seeming Misfortune for Osteosarcoma of Mandible-Rare Case Report.早期诊断：下颌骨肉瘤的一个看似不幸的情况——罕见病例报告
Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):748-751. doi: 10.1007/s12070-018-1534-x. Epub 2018 Nov 20.
5
Pan-cancer RNA-seq data stratifies tumours by some hallmarks of cancer.泛癌 RNA-seq 数据通过癌症的一些标志性特征对肿瘤进行分类。
J Cell Mol Med. 2020 Jan;24(1):418-430. doi: 10.1111/jcmm.14746. Epub 2019 Nov 15.
6
Growth hormone receptor promotes osteosarcoma cell growth and metastases.生长激素受体促进骨肉瘤细胞生长和转移。
FEBS Open Bio. 2020 Jan;10(1):127-134. doi: 10.1002/2211-5463.12761. Epub 2019 Dec 18.
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Brief Summary of the Most Important Molecular Genetic Methods (PCR, qPCR, Microarray, Next-Generation Sequencing, etc.).最重要的分子遗传学方法（聚合酶链式反应、定量聚合酶链式反应、微阵列、新一代测序等）简要概述。
Exp Suppl. 2019;111:33-52. doi: 10.1007/978-3-030-25905-1_4.
8
RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing.剪接体的 RNA 成分调节组织和癌症特异性的可变剪接。
Genome Res. 2019 Oct;29(10):1591-1604. doi: 10.1101/gr.246678.118. Epub 2019 Aug 21.
9
Primary osteosarcoma in elderly patients: A report of three cases.老年患者原发性骨肉瘤：三例报告
Oncol Lett. 2019 Aug;18(2):990-996. doi: 10.3892/ol.2019.10446. Epub 2019 Jun 7.
10
Aberrant alternative splicing in breast cancer.乳腺癌中的异常可变剪接。
J Mol Cell Biol. 2019 Oct 25;11(10):920-929. doi: 10.1093/jmcb/mjz033.
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