Oyedeji O A, Afolabi A A, Odeyemi A O, Kayode V O, Agelebe E
Department of Paediatrics and Child Health, Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Osun State, Nigeria.
Paediatric Unit, Morning Star International Hospital, D/Line, Port Harcourt, Nigeria.
Niger J Clin Pract. 2020 Aug;23(8):1061-1067. doi: 10.4103/njcp.njcp_359_19.
Atopy is poorly researched in HIV children living in the developing countries. There is no previous report on this subject in Nigeria and this pioneering study is undertaken to create an awareness of the burden of this disease among health practitioners.
The aim of this study was to document the atopic diseases present among HIV-infected children attending the antiretroviral (ARV) clinic of a Nigerian tertiary hospital.
Information was obtained from consecutive consenting caregiver/HIV-infected child attending the pediatric ARV clinic, by the use of a proforma specifically designed for the study. The data obtained were analyzed using Statistical Package for the Social Sciences (SPSS) software program, version 16.0.
Seventy patients were studied and their ages ranged between 2 and 17 years. These 70 were constituted by 34 (48.6%) boys and 36 (51.4%) girls. Ten (14.3%) of the 70 studied, had atopic diseases. Nine (12.9%) patients had allergic conjunctivitis and 1 (1.4%) had allergic rhinitis. The single patient with allergic rhinitis also had bronchial asthma. No case of atopic eczema, or food allergy was recorded. Atopic disease conditions were more commonly recorded among the male sex and those whose parents have atopic diseases (P < 0.05). Atopic diseases were also more common among children without advanced HIV diseases and those with eosinophilia. Cosmetic and psychological embarrassment from eye discoloration and itching were the negative impacts on the quality of living.
Allergic conjunctivitis is common in HIV-infected Nigerian children. Atopies are more common in boys and children with parental atopies.
在发展中国家，对感染艾滋病毒儿童的特应性疾病研究较少。尼日利亚此前尚无关于该主题的报告，开展这项开创性研究旨在提高医护人员对这种疾病负担的认识。
本研究旨在记录在尼日利亚一家三级医院抗逆转录病毒（ARV）诊所就诊的感染艾滋病毒儿童中存在的特应性疾病。
通过使用专门为该研究设计的表格，从连续同意参与的照顾者/感染艾滋病毒儿童处获取信息，这些儿童均在儿科抗逆转录病毒诊所就诊。使用社会科学统计软件包（SPSS）16.0版软件程序对获得的数据进行分析。
共研究了70名患者，年龄在2至17岁之间。其中34名（48.6%）为男孩，36名（51.4%）为女孩。在研究的70名患者中，有10名（14.3%）患有特应性疾病。9名（12.9%）患者患有过敏性结膜炎，1名（1.4%）患有过敏性鼻炎。患有过敏性鼻炎的唯一一名患者还患有支气管哮喘。未记录到特应性皮炎或食物过敏病例。特应性疾病在男性以及父母患有特应性疾病的患者中更为常见（P < 0.05）。特应性疾病在未患晚期艾滋病毒疾病的儿童和嗜酸性粒细胞增多的儿童中也更为常见。眼睛变色和瘙痒带来的外观和心理困扰对生活质量产生了负面影响。
过敏性结膜炎在感染艾滋病毒的尼日利亚儿童中很常见。特应性疾病在男孩和父母患有特应性疾病的儿童中更为常见。
