Hussain Malik Hatim, Iqbal Zafar, Mithani Muhammad Shoaib, Khan Muhammad Noman
Orthopaedics and Trauma, East Lancashire NHS Hospitals, Blackburn, GBR.
Emergency Medicine, California Institute of Behavioural Neurosciences and Psychology, Fairfield, USA.
Cureus. 2020 Jul 11;12(7):e9133. doi: 10.7759/cureus.9133.
Ganglioneuroblastoma, neuroblastoma, and ganglioneuroma (GN) are the tumors that arise from the neural crest cells. Of these, GN has the most benign origin without metastatic potential. The most common sites of their origin are the posterior mediastinum and retroperitoneum. Although the imaging studies, including CT, are available to detect these tumors, the definitive diagnosis can only be made by histological examination. We present a case of a 40-year-old woman with a retroperitoneal GN causing longstanding, gradually increasing, uncontrolled abdominal pain due to its pressure effect on the pancreas, duodenum, and right kidney with the displacement of the inferior vena cava. An exploratory laparotomy was performed, and the mass was removed. Histopathology confirmed the benign nature of the mass (a GN). These tumors are rarely malignant and mostly asymptomatic. However, in our case, abdominal pain was affecting the patient's life. After a discussion with the patient, an elective surgical procedure was performed, and the patient was symptom-free postoperatively and able to resume her regular routine.
神经节神经母细胞瘤、神经母细胞瘤和神经节瘤（GN）是起源于神经嵴细胞的肿瘤。其中，GN起源最良性，无转移潜能。它们最常见的起源部位是后纵隔和腹膜后。尽管包括CT在内的影像学检查可用于检测这些肿瘤，但最终诊断只能通过组织学检查来确定。我们报告一例40岁女性，患有腹膜后GN，因其对胰腺、十二指肠和右肾的压迫作用以及下腔静脉移位，导致长期、逐渐加重且难以控制的腹痛。进行了剖腹探查术，并切除了肿块。组织病理学证实肿块（GN）为良性。这些肿瘤很少恶变，大多无症状。然而，在我们的病例中，腹痛影响了患者的生活。与患者讨论后，进行了择期手术，患者术后无症状，能够恢复正常生活。
