Lam Germain, McCarthy Rowan, Haider Rana
General Internal Medicine, Withybush General Hospital, Haverfordwest, Pembrokeshire, United Kingdom.
Eur J Case Rep Intern Med. 2020 Jul 14;7(8):001779. doi: 10.12890/2020_001779. eCollection 2020.
It is increasingly recognised that patients with severe COVID-19 infection have a significant risk of thromboembolic events. We describe a patient who rapidly deteriorated due to severe infection with COVID-19, and developed priapism in the last days of his life. We believe development of priapism may be associated with a prothrombotic state secondary to COVID-19 infection. This case report supports the widely reported increased incidence of thrombosis in patients with severe COVID-19 infection.
Prophylactic doses of anticoagulation may not be sufficient in patients with severe COVID-19 infection, but clinical trials of therapeutic dose anticoagulation are underway.Physicians should be vigilant and have a high suspicion for thrombosis in all patients with COVID-19 infection, even those who are anticoagulated.Presentations of thromboembolism and microemboli may be atypical.
越来越多的人认识到，重症新型冠状病毒肺炎（COVID-19）感染患者有发生血栓栓塞事件的重大风险。我们描述了一名因COVID-19严重感染而迅速恶化的患者，在其生命的最后几天出现了阴茎异常勃起。我们认为阴茎异常勃起的发生可能与COVID-19感染继发的血栓前状态有关。本病例报告支持了广泛报道的重症COVID-19感染患者血栓形成发生率增加的情况。
对于重症COVID-19感染患者，预防性抗凝剂量可能不足，但治疗性抗凝剂量的临床试验正在进行中。医生应对所有COVID-19感染患者保持警惕，高度怀疑血栓形成，即使是那些已经接受抗凝治疗的患者。血栓栓塞和微栓塞的表现可能不典型。
