Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, P. R. China.
State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry Chinese Academy of Sciences, Changchun 130022, P. R. China.
Dalton Trans. 2020 Aug 25;49(33):11493-11497. doi: 10.1039/d0dt02584d.
Herein, we provide a new and facile strategy to successfully overcome the inherent aggregation-caused quenching effect and hydrophobicity that exist in traditional PSs by the introduction of sodium salts. The obtained water-soluble Ir(iii) complexes as carrier-free and pure nanoparticle photosensitizers exhibit excellent performance in photodynamic therapy and cell imaging.
在此，我们提供了一种新的简便策略，通过引入钠盐成功克服了传统 PS 中固有的聚集引起的猝灭效应和疏水性。所得的水溶性 Ir(iii)配合物作为无载体的纯纳米颗粒光敏剂，在光动力疗法和细胞成像中表现出优异的性能。
