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胰岛素依赖型糖尿病女性的泌乳结局。

Lactation outcome in insulin-dependent diabetic women.

作者信息

Ferris A M, Dalidowitz C K, Ingardia C M, Reece E A, Fumia F D, Jensen R G, Allen L H

机构信息

Nutritional Sciences Department, University of Connecticut, Storrs.

出版信息

J Am Diet Assoc. 1988 Mar;88(3):317-22.

PMID:3279099
Abstract

To document the incidence and management of breast feeding among women with insulin-dependent diabetes mellitus (IDDM), 30 IDDM mothers and 30 controls were followed from birth of their infants to 6 weeks postpartum. The researchers interviewed the mothers in the hospital and by telephone at 1, 2, and 6 weeks postpartum. Fifty-three percent of the IDDM women and 57% of the general hospital population intended to breast feed. Because of the need for neonatal observation for hypoglycemia, most IDDM mothers were separated from their infants for the first 2 days. After 1 week, as many IDDM mothers as controls nursed. Initially, no differences in breast-feeding problems were found between the groups, but between 2 and 6 weeks postpartum, two IDDM nursing mothers but none of the controls experienced clinically diagnosed mastitis. A daily diet prescription of 31 kcal per kilogram of maternal body weight was associated with IDDM mothers' ability to sustain lactation, in contrast with 25 kcal per kilogram of maternal weight for IDDM mothers who stopped nursing. Six-week postpartum fasting plasma glucose levels of IDDM mothers who exclusively breast fed were significantly lower (4.6 +/- 2.2 mmol/L [82 +/- 40 mg/dl]) than the glucose levels of the women who stopped nursing (8.1 +/- 2.1 mmol/L [145 +/- 37 mg/dl]) or the glucose levels of the IDDM mothers who chose to bottle feed (6.7 +/- 1.7 mmol/L [120 +/- 30 mg/dl]). It appears that adequate maternal calories, blood sugar control, early breast stimulation, and mastitis monitoring are necessary for optimal lactation outcome in insulin-dependent diabetic women.

摘要

为记录胰岛素依赖型糖尿病(IDDM)女性的母乳喂养发生率及管理情况,对30位患有IDDM的母亲和30位对照者从其婴儿出生至产后6周进行了跟踪研究。研究人员在医院对母亲们进行了访谈,并在产后1周、2周和6周通过电话进行随访。53%的IDDM女性和57%的普通医院产妇打算进行母乳喂养。由于需要对新生儿进行低血糖观察,大多数IDDM母亲在产后头2天与婴儿分离。1周后,进行母乳喂养的IDDM母亲与对照者数量相当。最初,两组之间在母乳喂养问题上未发现差异,但在产后2至6周期间,有两位进行母乳喂养的IDDM母亲出现了临床诊断的乳腺炎,而对照者中无人出现。与停止母乳喂养的IDDM母亲每千克体重25千卡的饮食处方相比,每千克母亲体重31千卡的日常饮食处方与IDDM母亲维持泌乳的能力相关。纯母乳喂养的IDDM母亲产后6周的空腹血糖水平显著低于停止母乳喂养的女性(4.6±2.2毫摩尔/升[82±40毫克/分升])或选择人工喂养的IDDM母亲的血糖水平(6.7±1.7毫摩尔/升[120±30毫克/分升])。对于胰岛素依赖型糖尿病女性,充足的母体热量、血糖控制、早期乳房刺激以及乳腺炎监测似乎是实现最佳泌乳结果所必需的。

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