Wieczorek Z, Skibiński G, Zwoliński J
Arch Immunol Ther Exp (Warsz). 1977;25(1):63-8.
Rosette inhibitory factor (RIF) in serum of patients suffering from active pulmonary tuberculosis, after in vitro contact with lymphocytes from healthy subjects, inhibits spontaneous rosette formation of these lymphocytes with sheep red blood cells (SRBC). RIF is not a C-reactive protein. By the use of chromatography on Sephadex G-200 and single analytic flotation, RIF was found to be contained in the beta-lipoprotein fraction. The presumable mechanism of formation of this factor and suggestions concerning its action on T cells are discussed.
活动性肺结核患者血清中的玫瑰花结抑制因子（RIF），在体外与健康受试者的淋巴细胞接触后，可抑制这些淋巴细胞与绵羊红细胞（SRBC）的自发玫瑰花结形成。RIF不是C反应蛋白。通过在Sephadex G - 200上进行色谱分析和单分析浮选，发现RIF存在于β-脂蛋白组分中。本文讨论了该因子形成的可能机制及其对T细胞作用的相关建议。
