妊娠微生物组与早产。
The pregnancy microbiome and preterm birth.
作者信息
Bayar Erna, Bennett Phillip R, Chan Denise, Sykes Lynne, MacIntyre David A
机构信息
Imperial College Parturition Research Group, Institute for Reproductive and Developmental Biology, Imperial College London, Du Cane Road, London, W12 0HS, UK.
March of Dimes European Preterm Birth Research Centre, Imperial College London, London, UK.
出版信息
Semin Immunopathol. 2020 Aug;42(4):487-499. doi: 10.1007/s00281-020-00817-w. Epub 2020 Aug 14.
Abstract
Preterm birth is a global health concern and continues to contribute to substantial neonatal morbidity and mortality despite advances in obstetric and neonatal care. The underlying aetiology is multi-factorial and remains incompletely understood. In this review, the complex interplay between the vaginal microbiome in pregnancy and its association with preterm birth is discussed in depth. Advances in the study of bacteriology and an improved understanding of the human microbiome have seen an improved awareness of the vaginal microbiota in both health and in disease.
摘要
早产是一个全球关注的健康问题，尽管产科和新生儿护理有所进步，但它仍然导致大量新生儿发病和死亡。其潜在病因是多因素的，仍未完全了解。在这篇综述中，将深入讨论孕期阴道微生物群之间的复杂相互作用及其与早产的关联。细菌学研究的进展以及对人类微生物群的更好理解，使人们对健康和疾病状态下的阴道微生物群有了更高的认识。
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