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子宫动脉多普勒在早发型和晚发型重度子痫前期中的预测作用。

Prognostic role of uterine artery Doppler in early- and late-onset preeclampsia with severe features.

机构信息

Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

Department of Neonatology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

出版信息

J Ultrasound. 2021 Sep;24(3):303-310. doi: 10.1007/s40477-020-00524-0. Epub 2020 Aug 14.

DOI:10.1007/s40477-020-00524-0
PMID:32797405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8363681/
Abstract

OBJECTIVE

To correlate uterine artery Doppler findings with maternal and neonatal outcomes in early- and late-onset preeclampsia with severe features.

METHODOLOGY

Doppler scan was done in both uterine arteries. Maternal and neonatal outcomes in women with abnormal and normal Doppler results were compared.

RESULTS

Abnormal Doppler results were present in 45 women (75%). Thirty-four (56.7%) women had abnormal RI, 19 (31.6%) had abnormal PI, and 36 (60%) had diastolic notch. Of the women who participated in the study, 21.6% developed maternal complications, and the majority belonged to the early-onset severe preeclampsia group. Diastolic notch was twofold more frequent in the early group. RI was abnormal in 63% of the early-onset and 50% of the late-onset group.

CONCLUSION

Pregnancies with early-onset preeclampsia who had abnormal uterine artery Doppler findings were at high risk for both maternal and neonatal complications, whereas those who had late-onset preeclampsia with abnormal Doppler findings only had an increased risk of perinatal complications.

摘要

目的

探讨早发型和晚发型重度特征子痫前期患者子宫动脉多普勒表现与母婴结局的相关性。

方法

对所有患者的子宫动脉进行多普勒扫描。比较子宫动脉多普勒结果异常和正常患者的母婴结局。

结果

45 例(75%)患者子宫动脉多普勒结果异常。34 例(56.7%)患者 RI 值异常,19 例(31.6%)患者 PI 值异常,36 例(60%)患者出现舒张末期切迹。研究中,21.6%的患者出现了母体并发症,大多数属于早发型重度子痫前期组。早发型组出现舒张末期切迹的比例是晚发型组的两倍。早发型组中,63%的患者 RI 值异常,晚发型组中,50%的患者 RI 值异常。

结论

早发型子痫前期患者子宫动脉多普勒检查异常,其母婴均有较高的并发症风险,而晚发型子痫前期患者子宫动脉多普勒检查异常,仅围产儿并发症风险增加。

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Third-trimester uterine artery Doppler measurement and maternal postpartum outcome among patients with severe pre-eclampsia.重度子痫前期患者孕晚期子宫动脉多普勒测量与产后母儿结局
Int J Gynaecol Obstet. 2015 Oct;131(1):49-53. doi: 10.1016/j.ijgo.2015.03.045. Epub 2015 Jun 18.
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Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy.妊娠期高血压。美国妇产科医师学会妊娠期高血压特别工作组报告
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The prognostic role of uterine artery Doppler investigation in patients with severe early-onset preeclampsia.子宫动脉多普勒检查在重度早发型子痫前期患者中的预测作用。
Am J Obstet Gynecol. 2010 Jun;202(6):559.e1-4. doi: 10.1016/j.ajog.2010.01.048. Epub 2010 Mar 29.
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The prognostic role of uterine artery Doppler studies in patients with late-onset preeclampsia.子宫动脉多普勒检查在晚发型子痫前期患者中的预后作用。
Am J Obstet Gynecol. 2009 Jul;201(1):36.e1-5. doi: 10.1016/j.ajog.2009.02.024. Epub 2009 Apr 19.
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Increased uterine artery vascular impedance is related to adverse outcome of pregnancy but is present in only one-third of late third-trimester pre-eclamptic women.子宫动脉血管阻力增加与不良妊娠结局相关,但仅在三分之一的孕晚期子痫前期妇女中出现。
Ultrasound Obstet Gynecol. 2005 May;25(5):459-63. doi: 10.1002/uog.1895.
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