Yuan Dongqing, Zhang Weiwei, Yuan Songtao, Xie Ping, Liu Qinghuai
Department of Ophthalmology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, People's Republic of China.
Clin Ophthalmol. 2020 Jul 23;14:2079-2085. doi: 10.2147/OPTH.S259642. eCollection 2020.
To evaluate the vision-related quality of life of vitrectomy combined with autologous internal limiting membrane (ILM) transplantation for refractory macular holes (MHs).
There were 40 eyes with refractory MHs included, and all eyes received 23 G vitrectomy and ILM peeling with autologous ILM transplantation. Preoperative and postoperative basic conditions were recorded. The Chinese version of the vision-related quality-of-life scale was used to evaluate patients after operation. Quality of life, postoperative visual acuity, and size of MHs before operation were assessed with Spearman rank correlations.
All patients were followed up for 3 months after surgery. Mean postoperative best-corrected visual acuity had significantly improved after surgery. Vision-related quality of life of patients after surgery was closely related to the MH index, but negatively correlated with best-corrected visual acuity before and after surgery.
The anatomical structure of refractory MHs with ILM peeling combined with autologous ILM transplantation was largely reduced, and the visual acuity of patients improved significantly.
评估玻璃体切除术联合自体内界膜（ILM）移植治疗难治性黄斑裂孔（MHs）的视力相关生活质量。
纳入40只难治性MHs眼，所有患眼均接受23G玻璃体切除术及自体ILM剥离联合ILM移植。记录术前和术后的基本情况。术后使用中文版视力相关生活质量量表对患者进行评估。采用Spearman等级相关性分析评估生活质量、术后视力和术前MHs大小。
所有患者术后随访3个月。术后平均最佳矫正视力有显著改善。患者术后视力相关生活质量与MH指数密切相关，但与术前和术后最佳矫正视力呈负相关。
ILM剥离联合自体ILM移植可使难治性MHs的解剖结构显著缩小，患者视力明显提高。
