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采用上睑金片植入术治疗的面神经麻痹未愈合并暴露性角膜病变患者的生活质量

Quality of Life in Patients with Unresolved Facial Nerve Palsy and Exposure Keratopathy Treated by Upper Eyelid Gold Weight Loading.

作者信息

Nowak-Gospodarowicz Izabela, Różycki Radosław, Rękas Marek

机构信息

Department of Ophthalmology, Military Institute of Medicine, Warsaw 04-141, Poland.

出版信息

Clin Ophthalmol. 2020 Aug 5;14:2211-2222. doi: 10.2147/OPTH.S254533. eCollection 2020.

Abstract

BACKGROUND

Loading of the upper eyelid with gold weights is a well-established procedure for the correction of paralytic lagophthalmos. There is no reliable research evaluating the results of this treatment from the patients' viewpoint.

AIM

The aim of this research was to evaluate quality of life (QOL) domains through two standardized questionnaires (SF-36 and NEI-VFQ39) in patients treated by upper eyelid gold weight loading compared to healthy individuals (the "healthy" group) as well as patients with other ophthalmologic conditions (the "sick" group).

PATIENTS AND METHODS

This prospective comparative clinical study of 416 surveys was conducted in 2012-2018. The study group includes 59 people: 40 women, 19 men aged 55.5 ± 17.4 treated with gold weights for corneal complications due to unresolved facial nerve palsy. General QOL was assessed using the SF-36 questionnaire. Eye-related QOL was assessed through the NEI-VFQ39 questionnaire. The results were compared with those obtained in 2 control groups: the "healthy" and the "sick," 53 individuals each.

RESULTS

A statistically significant increase in QOL domains was noted in patients with facial nerve palsy after treatment (p<0.001). No statistically significant differences were found in categories defining the Physical Component Score in these patients as compared to those from the "sick" control group (p = 0.95). After surgery, the results of the Mental Component Score were comparable to those in the "healthy" control group (p = 0.51). The eye-related health scores changed significantly after surgery and differed significantly compared to the "sick" control group (p <0.05); however, they did not reach the level of the "healthy" control group (p <0.001).

CONCLUSION

Patients with untreated facial nerve palsy had the lowest QOL levels among all individuals involved in this study. Treatment of lagophthalmos by gold weights significantly improved their QOL, with the greatest impact on mental aspects of health.

摘要

背景

在上眼睑植入金片是矫正麻痹性兔眼的一种成熟方法。目前尚无从患者角度评估该治疗效果的可靠研究。

目的

本研究旨在通过两份标准化问卷(SF - 36和NEI - VFQ39)评估接受上眼睑金片植入治疗的患者与健康个体(“健康”组)以及患有其他眼科疾病的患者(“患病”组)相比的生活质量(QOL)领域。

患者与方法

这项前瞻性比较临床研究在2012 - 2018年进行了416次调查。研究组包括59人:40名女性,19名男性,年龄55.5±17.4岁,因面神经麻痹未愈导致角膜并发症而接受金片植入治疗。使用SF - 36问卷评估总体生活质量。通过NEI - VFQ39问卷评估与眼睛相关的生活质量。将结果与两个对照组(各53人)的结果进行比较:“健康”组和“患病”组。

结果

治疗后面神经麻痹患者的生活质量领域有统计学显著提高(p<0.001)。与“患病”对照组相比,这些患者在定义身体成分得分的类别中未发现统计学显著差异(p = 0.95)。手术后,心理成分得分结果与“健康”对照组相当(p = 0.51)。手术后与眼睛相关的健康得分有显著变化,与“患病”对照组相比有显著差异(p <0.05);然而,它们未达到“健康”对照组的水平(p <0.0)。

结论

在本研究涉及的所有个体中,未经治疗的面神经麻痹患者生活质量水平最低。金片植入治疗兔眼显著改善了他们的生活质量,对健康的心理方面影响最大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5514/7415438/33352e0d1c63/OPTH-14-2211-g0001.jpg

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