Sheikhpour Mojgan, Arabi Mohadeseh, Kasaeian Alibakhsh, Rokn Rabei Ali, Taherian Zahra
Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran.
Nanotechnol Sci Appl. 2020 Jul 24;13:47-59. doi: 10.2147/NSA.S260374. eCollection 2020.
Recently, suspensions of several nanoparticles or nanocomposites have attained a vast field of application in biomedical research works in some specified conditions and clinical trials. These valuable suspensions, which allow the nanoparticles to disperse and act in homogenous and stable media, are named as nanofluids. Several studies have introduced the advantages of nanofluids in biomedical approaches in different fields. Few review articles have been reported for presenting an overview of the wide biomedical applications of nanofluids, such as diagnosis and therapy. The review is focused on nanosuspensions, as the nanofluids with solid particles. Major applications are focused on nanosuspension, which is the main type of nanofluids. So, concise content about major biomedical applications of nanofluids in drug delivery systems, imaging, and antibacterial activities is presented in this paper. For example, applying magnetic nanofluid systems is an important route for targeted drug delivery, hyperthermia, and differential diagnosis. Also, nanofluids could be used as a potential antibacterial agent to overcome antibiotic resistance. This study could be useful for presenting the novel and applicable methods for success in current medical practice.
最近，几种纳米颗粒或纳米复合材料的悬浮液在某些特定条件下的生物医学研究工作和临床试验中获得了广泛的应用领域。这些宝贵的悬浮液能使纳米颗粒在均匀稳定的介质中分散并发挥作用，被称为纳米流体。多项研究介绍了纳米流体在不同领域生物医学方法中的优势。很少有综述文章报道纳米流体在生物医学广泛应用方面的概述，如诊断和治疗。本综述聚焦于纳米悬浮液，即含有固体颗粒的纳米流体。主要应用集中在纳米悬浮液，它是纳米流体的主要类型。因此，本文介绍了纳米流体在药物递送系统、成像和抗菌活性等主要生物医学应用方面的简要内容。例如，应用磁性纳米流体系统是靶向药物递送、热疗和鉴别诊断的重要途径。此外，纳米流体可作为一种潜在的抗菌剂来克服抗生素耐药性。本研究对于展示当前医学实践中成功的新颖且适用的方法可能是有用的。
