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与发育正常的同龄人相比,通过自我报告和家长报告发现,患有自闭症谱系障碍的青少年早期抑郁症状更严重。

Higher depressive symptoms in early adolescents with Autism Spectrum Disorder by self- and parent-report compared to typically-developing peers.

作者信息

Schwartzman Jessica M, Corbett Blythe A

机构信息

Vanderbilt University Medical Center, 1601 23 Avenue South, Nashville, TN, United States 37212.

Vanderbilt Kennedy Center, 110 Magnolia Circle, Nashville, TN, United States 37203.

出版信息

Res Autism Spectr Disord. 2020 Sep;77. doi: 10.1016/j.rasd.2020.101613. Epub 2020 Jul 17.

Abstract

BACKGROUND

Depression is more prevalent among male early adolescents with Autism Spectrum Disorder (ASD) than their typically- developing (TD) peers, but findings are limited to two male-only studies. Therefore, a broader understanding of depressive symptoms among both male and female early adolescents with ASD in larger samples is needed. Self- and parent-ratings are frequently used, yet rater differences may emerge and provide unique insights.

METHOD

Ratings of adolescent depressive symptoms were examined among 230 early adolescents (10:0-13:5 years) with and without ASD using self- (Children's Depression Inventory, Second Edition; CDI-2) and parent- report (Child Behavior Checklist; CBCL) measures. The influence of diagnostic group (ASD vs. TD) and rater (early adolescent vs. parent) on ratings were examined with Full Scale IQ and sex as covariates. Additionally, the reliability and strength of agreement between raters were examined.

RESULTS

Higher depressive symptoms were reported by both raters in the ASD group (Borderline range) compared to the TD group (Average range). The interaction of diagnostic group and rater was nonsignificant, but significant main effects emerged. Sex was a significant covariate, but Full Scale IQ was not. The reliability and strength of agreement between raters in the ASD group only were not significant.

CONCLUSIONS

Findings suggest that depressive symptoms may be higher in both male and female early adolescents with ASD across self- and parent- reports. However, measurement of depression in ASD may be complicated by nonsignificant reliability and strength of agreement between raters. Results have implications for screening and intervention for early adolescents with ASD.

摘要

背景

与发育正常的同龄人相比,患有自闭症谱系障碍(ASD)的男性青少年早期抑郁症更为普遍,但研究结果仅限于两项仅针对男性的研究。因此,需要在更大的样本中更广泛地了解患有ASD的男性和女性青少年早期的抑郁症状。经常使用自我评分和家长评分,但评分者之间可能会出现差异,并提供独特的见解。

方法

使用自我报告(儿童抑郁量表第二版;CDI - 2)和家长报告(儿童行为检查表;CBCL)对230名年龄在10:0至13:5岁之间、患有和未患有ASD的青少年早期进行抑郁症状评分。以全量表智商和性别作为协变量,研究诊断组(ASD与发育正常;TD)和评分者(青少年早期与家长)对评分的影响。此外,还研究了评分者之间的信度和一致性强度。

结果

与TD组(平均范围)相比,ASD组(临界范围)的两个评分者报告的抑郁症状都更高。诊断组和评分者的交互作用不显著,但出现了显著的主效应。性别是一个显著的协变量,但全量表智商不是。仅ASD组评分者之间的信度和一致性强度不显著。

结论

研究结果表明,无论是自我报告还是家长报告,患有ASD的男性和女性青少年早期的抑郁症状可能都更高。然而,ASD中抑郁症的测量可能因评分者之间信度和一致性强度不显著而变得复杂。研究结果对患有ASD的青少年早期的筛查和干预具有启示意义。

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