Alves Jéssica Aparecida, Abrão Fariza, da Silva Moraes Thaís, Damasceno Jaqueline Lopes, Dos Santos Moraes Marcos Fernando, Sola Veneziani Rodrigo Cassio, Ambrósio Sérgio Ricardo, Bastos Jairo Kenupp, Dantas Miranda Mayker Lázaro, Gomes Martins Carlos Henrique
Research Laboratory of Applied Microbiology, University of Franca, Franca, SP, Brazil.
Nucleus of Research in Sciences & Technology, University de Franca, Franca, SP, Brazil.
Future Sci OA. 2020 May 29;6(7):FSO587. doi: 10.2144/fsoa-2020-0018.
This paper reports on the antimycobacterial activity of the oleoresins and extracts obtained from spp.
MATERIALS & METHODS: The minimum inhibitory concentration (MIC) and fractional inhibitory concentration index techniques helped to evaluate the effect of these oleoresins and extracts against six strains of mycobacteria that cause tuberculosis.
RESULTS & CONCLUSION: Among the assayed oleoresins and plant extracts, the , , and oleoresins provided the lowest MIC values against some of the tested strains. The combination of spp. samples with isoniazid did not evidence any synergistic action. Some spp. oleoresins may represent a future source for the discovery of new antimycobacterial drugs due to their low MIC values.
本文报道了从[具体物种]获得的油树脂和提取物的抗分枝杆菌活性。
最小抑菌浓度（MIC）和分数抑菌浓度指数技术有助于评估这些油树脂和提取物对六种引起结核病的分枝杆菌菌株的作用。
在所检测的油树脂和植物提取物中，[具体名称]、[具体名称]、[具体名称]和[具体名称]油树脂对一些测试菌株的MIC值最低。[具体物种]样品与异烟肼的组合未显示出任何协同作用。由于其低MIC值，一些[具体物种]油树脂可能代表了发现新型抗分枝杆菌药物的未来来源。
