将属作为抗真菌药物新来源的研究。 （注：原文中“antimycobaterial”有误，推测应为“antimycobacterial”，意为“抗分枝杆菌的”，但按照指令要求未作修改直接翻译，这里译文与原文对应，若修正错误单词后译文为“将属作为抗分枝杆菌药物新来源的研究” ）
Investigation of genus as a new source of antimycobaterial agents.
作者信息
Alves Jéssica Aparecida, Abrão Fariza, da Silva Moraes Thaís, Damasceno Jaqueline Lopes, Dos Santos Moraes Marcos Fernando, Sola Veneziani Rodrigo Cassio, Ambrósio Sérgio Ricardo, Bastos Jairo Kenupp, Dantas Miranda Mayker Lázaro, Gomes Martins Carlos Henrique
机构信息
Research Laboratory of Applied Microbiology, University of Franca, Franca, SP, Brazil.
Nucleus of Research in Sciences & Technology, University de Franca, Franca, SP, Brazil.
出版信息
Future Sci OA. 2020 May 29;6(7):FSO587. doi: 10.2144/fsoa-2020-0018.
Abstract
AIM
This paper reports on the antimycobacterial activity of the oleoresins and extracts obtained from spp.
MATERIALS & METHODS: The minimum inhibitory concentration (MIC) and fractional inhibitory concentration index techniques helped to evaluate the effect of these oleoresins and extracts against six strains of mycobacteria that cause tuberculosis.
RESULTS & CONCLUSION: Among the assayed oleoresins and plant extracts, the , , and oleoresins provided the lowest MIC values against some of the tested strains. The combination of spp. samples with isoniazid did not evidence any synergistic action. Some spp. oleoresins may represent a future source for the discovery of new antimycobacterial drugs due to their low MIC values.
摘要
目的
本文报道了从[具体物种]获得的油树脂和提取物的抗分枝杆菌活性。
材料与方法
最小抑菌浓度（MIC）和分数抑菌浓度指数技术有助于评估这些油树脂和提取物对六种引起结核病的分枝杆菌菌株的作用。
结果与结论
在所检测的油树脂和植物提取物中，[具体名称]、[具体名称]、[具体名称]和[具体名称]油树脂对一些测试菌株的MIC值最低。[具体物种]样品与异烟肼的组合未显示出任何协同作用。由于其低MIC值，一些[具体物种]油树脂可能代表了发现新型抗分枝杆菌药物的未来来源。
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