Anwar M, Brockmann T, Walckling M, Fuchsluger T A
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Doberaner Str. 140, 18057, Rostock, Deutschland.
Ophthalmologe. 2021 Aug;118(8):838-841. doi: 10.1007/s00347-020-01202-6.
A 72-year-old female patient developed bilateral secondary iridocorneal angle-closure glaucoma with uveal effusion syndrome after uncomplicated cataract surgery. The postoperative intake of acetazolamide was identified as causative for the development of the effusion syndrome. Taking a sulfonamide-free systemic and local intraocular pressure lowering and anti-inflammatory treatment into account, a rapid improvement of the ocular manifestation was achieved. The case illustrates a rare but clinically severe adverse effect of acetazolamide and outlines efficient treatment options.
一名72岁女性患者在白内障手术无并发症后发生双侧继发性虹膜角膜角关闭性青光眼并伴有葡萄膜渗漏综合征。术后服用乙酰唑胺被确定为渗漏综合征发生的原因。考虑到采用无磺胺类药物的全身和局部降低眼压及抗炎治疗，眼部症状迅速得到改善。该病例说明了乙酰唑胺一种罕见但临床上严重的不良反应，并概述了有效的治疗选择。
