Department of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Department of Prosthodontics, Dental Clinic 2, University of Erlangen-Nuremberg, Erlangen, Germany.
J Xray Sci Technol. 2020;28(6):1141-1155. doi: 10.3233/XST-200690.
BACKGROUND/OBJECTIVE: In this retrospective study, we aimed to investigate a new 3D evaluation method for evaluating bone regeneration after cystectomy of odontogenic cysts.
The study included 26 patients who underwent cystectomies between 2012 and 2017 and had received either fillings or non-fillings with autologous iliac crest. Bony regeneration was analyzed using 3D imaging software and comparing identical regions of interest (ROIs) that were determined by exact overlays of the postoperative cone beam computer tomography (CBCT) or computer tomography (CT) images. Outcome measures, including volume changes according to the defect size and configuration, patient age, the entity and distribution of the cysts, were collected.
Twenty-six patients (5 women and 21 men) had 30 defects, including nine keratocysts, seven radicular cysts and 14 dentigerous cysts. A total of 73% of the defects were in the mandible. The mean 3D follow-up time was 12 months. According to the 3D evaluation of bony regeneration, the defect size and configuration showed no significant differences between the groups (filled or non-filled with 15 defects per group).
By establishing a standardized 3D method for evaluating bone regeneration, healing can be better monitored and evaluated.
背景/目的：在这项回顾性研究中，我们旨在研究一种新的 3D 评价方法，用于评估牙源性囊肿切除术后的骨再生情况。
本研究纳入了 2012 年至 2017 年间接受囊肿切除术且接受或未接受自体髂嵴填充的 26 例患者。使用 3D 成像软件分析骨再生情况，并通过精确重叠术后锥形束计算机断层扫描（CBCT）或计算机断层扫描（CT）图像来比较相同的感兴趣区域（ROI）。收集了包括根据缺损大小和形态、患者年龄、囊肿的实体和分布而变化的体积等结果测量指标。
26 例患者（5 名女性和 21 名男性）有 30 个缺损，包括 9 个角化囊肿、7 个根囊肿和 14 个含牙囊肿。73%的缺损位于下颌骨。3D 随访时间平均为 12 个月。根据骨再生的 3D 评价，填充组和未填充组的缺损大小和形态无显著差异（每组各有 15 个缺损）。
通过建立一种标准化的 3D 方法来评估骨再生，可以更好地监测和评估愈合情况。
