Chaushu Gabi, Reiser Vadim, Rosenfeld Eli, Masri Daya, Chaushu Liat, Čandrlić Marija, Rider Patrick, Perić Kačarević Željka
Department of Oral and Maxillofacial Surgery, Rabin Medical Center, Beilinson Campus, Petah Tikva 49100, Israel.
Department of Oral and Maxillofacial Surgery, The Maurice and Gabriela Goldschleger School of Dental Medicine, Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Healthcare (Basel). 2025 May 6;13(9):1068. doi: 10.3390/healthcare13091068.
Periapical cysts are the most common odontogenic cysts, often resulting in large bone defects. Guided tissue regeneration techniques support tissue healing by means of membranes and bone grafts. The present case report evaluates for the first time clinical application of a resorbable magnesium membrane in guided bone regeneration (GBR) following cystectomy.
A 35-year-old male patient presented with a large periapical cystic lesion in the maxillary anterior region. Treatment involved marsupialization followed by cyst enucleation and GBR using a resorbable magnesium membrane and bovine xenograft. The magnesium membrane served as a structural support to bridge the bony discontinuity in the palatal bone. Cone-beam computed tomography (CBCT) was used for diagnosis, treatment planning, and follow-up assessments. At 16 months post-treatment, CBCT imaging revealed significant bone regeneration, with restoration of the palatal contour and cortication of the palatal wall. Clinical examination showed asymptomatic teeth with normal mobility and optimal soft tissue healing.
This case demonstrates the potential of resorbable magnesium membranes in managing large periapical defects, offering a promising alternative to traditional GBR materials by combining mechanical strength with complete resorption, therefore eliminating the need for membrane removal surgery. However, future studies on larger patient samples should focus on confirming the long-term outcomes of this approach and investigating patient-specific factors that are important in choosing effective treatment options.
根尖囊肿是最常见的牙源性囊肿，常导致大面积骨缺损。引导组织再生技术通过膜和骨移植来支持组织愈合。本病例报告首次评估了可吸收镁膜在囊肿切除术后引导骨再生（GBR）中的临床应用。
一名35岁男性患者上颌前部出现一个大的根尖囊性病变。治疗包括袋形术，随后进行囊肿摘除术，并使用可吸收镁膜和牛异种移植物进行引导骨再生。镁膜作为一种结构支撑物，用于桥接腭骨的骨不连续处。锥形束计算机断层扫描（CBCT）用于诊断、治疗计划制定和随访评估。治疗后16个月，CBCT成像显示骨再生显著，腭轮廓恢复，腭壁皮质化。临床检查显示牙齿无症状，松动度正常，软组织愈合良好。
本病例证明了可吸收镁膜在处理大面积根尖缺损方面的潜力，通过将机械强度与完全吸收相结合，为传统引导骨再生材料提供了一种有前景的替代方案，从而无需进行膜移除手术。然而，未来对更大患者样本的研究应集中于确认该方法的长期效果，并调查在选择有效治疗方案中重要的患者特异性因素。
