青少年和青年中艾滋病毒暴露前预防的启动:障碍与机遇

Initiation of HIV pre-exposure prophylaxis in adolescents and young adults: Barriers and opportunities.

作者信息

Mocorro Igor, Sandhu Prabjot Jodie, Rowniak Stefan, Leonard Adam

机构信息

University of San Francisco (USF), School of Nursing and Health Professions, San Francisco, California.

Jonas Nurse Leader Scholar-Jonas Philanthropies, New York, New York.

出版信息

J Am Assoc Nurse Pract. 2020 Aug 13;33(9):700-708. doi: 10.1097/JXX.0000000000000485.

Abstract

BACKGROUND

Adolescents and young adults (AYA) ages 13 to 24 years comprise a quarter of the new HIV diagnoses in the United States. Lack of access to HIV-preventive biomedical tools such as pre-exposure prophylaxis (PrEP) reduces opportunities to prevent HIV infection in this population. Initiating PrEP in AYA significantly reduces the negative health outcomes of HIV, but many providers are still reluctant to initiate PrEP in their AYA patients based on perceived threats and barriers.

OBJECTIVES

This review aims to highlight the barriers and opportunities for initiating PrEP services in AYA and provides recommendations for PrEP services in this population.

DATA SOURCES

Ten scholarly articles rated levels IIA through IIIB were identified using the Johns Hopkins Evidence-Based Practice ratings. These included quasi-experimental and nonexperimental publications. Both quantitative and qualitative data contributed to identifying perceived barriers, opportunities, and recommendations for increased PrEP access and prescription in AYA.

CONCLUSIONS

Pre-exposure prophylaxis is a vital component of a robust HIV prevention program. Themes that emerged hindering optimal PrEP utilization in AYA included provider-related barriers (e.g., knowledge deficit, lack of familiarity with PrEP guidelines, and protocols), patient-related barriers (e.g., lack of awareness, confidentiality issue, and HIV stigma), and structure-related barriers (e.g., lack of AYA-friendly clinics and insurance coverage).

IMPLICATIONS FOR PRACTICE

Providers in any setting should be able identify at-risk AYA and prescribe PrEP accordingly. Nurse practitioners should make PrEP accessible to AYA by addressing the barriers to PrEP utilization, prescribing, and continuity of care. Nurse practitioner curriculum, training, and continuing education should include PrEP for AYA.

摘要

背景

13至24岁的青少年和青年(AYA)占美国新增艾滋病毒诊断病例的四分之一。无法获得暴露前预防(PrEP)等艾滋病毒预防生物医学工具减少了该人群预防艾滋病毒感染的机会。在青少年和青年中启动PrEP可显著降低艾滋病毒的负面健康后果,但许多医疗服务提供者仍因感知到的威胁和障碍而不愿为其青少年和青年患者启动PrEP。

目的

本综述旨在强调在青少年和青年中启动PrEP服务的障碍和机会,并为该人群的PrEP服务提供建议。

数据来源

使用约翰·霍普金斯循证实践评级确定了10篇IIA至IIIB级的学术文章。这些文章包括准实验性和非实验性出版物。定量和定性数据都有助于确定在青少年和青年中增加PrEP获取和处方的感知障碍、机会和建议。

结论

暴露前预防是强有力的艾滋病毒预防计划的重要组成部分。阻碍青少年和青年最佳使用PrEP出现的主题包括与医疗服务提供者相关的障碍(例如,知识不足、对PrEP指南和方案不熟悉)、与患者相关的障碍(例如,缺乏认识、保密问题和艾滋病毒污名)以及与结构相关的障碍(例如,缺乏适合青少年和青年的诊所和保险覆盖范围)。

对实践的启示

任何环境中的医疗服务提供者都应能够识别有风险的青少年和青年并相应地开具PrEP处方。执业护士应通过消除PrEP使用、处方和护理连续性方面的障碍,使青少年和青年能够获得PrEP。执业护士课程、培训和继续教育应包括针对青少年和青年的PrEP内容。

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