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IgG 对普氏立克次体的亲和力和血清中特异性 IgM 的存在,用于回顾性分析 1998 年俄罗斯流行性斑疹伤寒疫情。

Avidity of IgG to Rickettsia prowazekii and the presence of specific IgM in blood sera for retrospective analysis of the 1998 epidemic typhus outbreak in Russia.

机构信息

Laboratory for Epidemiology of Natural Focal Infections, Central Research Institute of Epidemiology, 111123 Moscow, Russia.

Omsk Research Institute of Natural Focal Infections, 644080 Omsk, Russia.

出版信息

J Microbiol Methods. 2020 Sep;176:106034. doi: 10.1016/j.mimet.2020.106034. Epub 2020 Aug 15.

Abstract

The authors applied a new methodological approach based not only on the study of IgM/IgG to Rickettsia prowazekii in sera, but also on the estimation of the avidity index of specific IgG. The data allowed the authors to draw new conclusions about the 1998 epidemic typhus outbreak in Russia.

摘要

作者应用了一种新的方法学方法,不仅研究了血清中的 IgM/IgG 与普氏立克次体的关系,还评估了特异性 IgG 的亲和指数。这些数据使作者能够对 1998 年俄罗斯爆发的斑疹伤寒疫情得出新的结论。

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