ARC Centre of Excellence in Convergent Bio-Nano Science & Technology and Drug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
Department of Chemistry, Department of Materials Science and Engineering, Texas A&M University, College Station, Texas 77807, United States.
ACS Appl Mater Interfaces. 2020 Sep 2;12(35):38845-38861. doi: 10.1021/acsami.0c07993. Epub 2020 Aug 24.
Emulsions are mixtures of two immiscible liquids in which droplets of one are dispersed in a continuous phase of the other. The most common emulsions are oil-water systems, which have found widespread use across a number of industries, for example, in the cosmetic and food industries, and are also of advanced scientific interest. In addition, the past decade has seen a significant increase in both the design and application of nonaqueous emulsions. This has been primarily driven by developments in understanding the mechanism of effective stabilization of oil-in-oil (o/o) systems, either using block copolymers (BCPs) or solid (Pickering) particles with appropriate surface functionality. These systems, as highlighted in this review, have enabled emergent applications in areas such as pharmaceutical delivery, energy storage, and materials design (e.g., polymerization, monolith, and porous polymer synthesis). These o/o emulsions complement traditional emulsions that utilize an aqueous phase and allow the use of materials incompatible with water. We assess recent advances in the preparation and stabilization of o/o emulsions, focusing on the identity of the stabilizer (BCP or particle), the interplay between stabilizer and oils, and highlighting applications and opportunities associated with o/o emulsions.
乳液是两种不混溶液体的混合物，其中一种液体的液滴分散在另一种液体的连续相中。最常见的乳液是油水体系，它在许多行业得到了广泛的应用，例如在化妆品和食品行业，并且也具有先进的科学意义。此外，过去十年中，无论是使用嵌段共聚物（BCP）还是具有适当表面功能的固体（Pickering）颗粒，对非水乳液的设计和应用都有了显著的增加。正如这篇综述所强调的那样，这些体系使得在药物输送、储能和材料设计（例如聚合、整体和多孔聚合物合成）等领域出现了新的应用。这些油包油乳液补充了利用水相的传统乳液，并允许使用与水不兼容的材料。我们评估了油包油乳液的制备和稳定化的最新进展，重点关注稳定剂（BCP 或颗粒）的特性、稳定剂和油之间的相互作用，并突出与油包油乳液相关的应用和机会。
