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颈动脉支架置入术后致命性颅内出血:三例报告及文献综述

Fatal intracranial hemorrhage after carotid artery stenting: Three case reports and a literature review.

作者信息

Zhou Yumiao, Zheng Chaobo, Chen Liang, Lin Yuanyuan

机构信息

Neurointerventional Department, Zhejiang Hospital, Hangzhou, China.

Internal Medicine Department, Zhejiang Greentown Cardiovascular Hospital, Hangzhou, China.

出版信息

J Int Med Res. 2020 Aug;48(8):300060520937576. doi: 10.1177/0300060520937576.

Abstract

INTRODUCTION

We herein describe three patients who developed fatal intracranial hemorrhage (ICH) after carotid artery stenting (CAS). We retrospectively reviewed 126 patients who underwent CAS from January 2016 to December 2018 and identified 3 patients (2.4%) (all male, mean age of 59 years) who developed ICH after CAS. Two of them developed left basal ganglia hemorrhage with extension into the ventricle and subarachnoid space, and the third patient developed primary ventricular bleeding. One hemorrhage occurred immediately after CAS, whereas the other two occurred 3 hours and 8 hours after the procedure, respectively. The mean stenosis of the treated carotid arteries was 91%. All three hemorrhages were fatal, and the mean time from hemorrhage to death was 50 hours.

CONCLUSION

ICH is a potentially fatal complication of CAS and often occurs several hours after the procedure. Headache, vomiting, and consciousness disorders are the most common symptoms of ICH. Careful screening to identify high-risk patients and strict management of perioperative blood pressure are important to prevent this complication.

摘要

引言

我们在此描述3例在颈动脉支架置入术(CAS)后发生致命性颅内出血(ICH)的患者。我们回顾性分析了2016年1月至2018年12月期间接受CAS的126例患者,确定了3例(2.4%)(均为男性,平均年龄59岁)在CAS后发生ICH的患者。其中2例发生左侧基底节出血并扩展至脑室和蛛网膜下腔,第3例患者发生原发性脑室出血。1例出血发生在CAS后即刻,另外2例分别发生在术后3小时和8小时。所治疗的颈动脉平均狭窄率为91%。所有3例出血均致命,从出血到死亡的平均时间为50小时。

结论

ICH是CAS的一种潜在致命并发症,且常发生在术后数小时。头痛、呕吐和意识障碍是ICH最常见的症状。仔细筛查以识别高危患者并严格管理围手术期血压对于预防该并发症很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dd5/7436830/6494f842a845/10.1177_0300060520937576-fig1.jpg

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