Department of Neurology, Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College), Nanchang, People's Republic of China.
Department of Neurology, Xiangya Hospital, Central South University, Jiangxi Hospital, National Regional Center for Neurological Diseases, Nanchang, People's Republic of China.
Medicine (Baltimore). 2024 Oct 4;103(40):e40032. doi: 10.1097/MD.0000000000040032.
Cerebral infarction is a common ischemic cerebrovascular disease, associated with high rates of morbidity, disability, and recurrence, that can seriously affect patient physical and mental health, as well as quality of life. Carotid artery stenosis is an independent risk factor of cerebral infarction. Following rapid developments in interventional technology and materials science, carotid artery stenting has arisen an important treatment option for carotid artery stenosis. However, surgery is associated with complications, such as postoperative hyperperfusion syndrome, which poses a serious threat to the life and health of patients. Staged angioplasty (SAP), that is, one-time revascularization of the carotid artery stenting, is divided into 2 stages. This method reduces the occurrence of hyperperfusion syndrome after stenting by increasing the ipsilateral cerebral blood flow in stages and gradually increasing the cerebral perfusion pressure.
Herein, we present 2 cases of elderly patients with severe carotid artery stenosis who underwent SAP to prevent hyperperfusion syndrome.
The final diagnosis was based on cervical vascular color Doppler ultrasonography, cervical vascular magnetic resonance angiography, and cerebral vascular digital subtraction angiography.
Both patients with severe carotid artery stenosis underwent a staged intravascular intervention.
Both patients were followed up for 1 year, with neither developing any new cerebral infarction or recurrent stent restenosis.
When treating SAP, it is crucial to consider that patients with unstable carotid plaques may not be suitable for staging. Additionally, during phase II carotid stenting, it is important to assess any changes in the arterial morphology and select the appropriate device accordingly.
脑梗死是一种常见的缺血性脑血管病,具有较高的发病率、致残率和复发率,严重影响患者的身心健康和生活质量。颈动脉狭窄是脑梗死的独立危险因素。随着介入技术和材料科学的快速发展,颈动脉支架置入术已成为治疗颈动脉狭窄的重要手段。但该手术与术后高灌注综合征等并发症相关,严重威胁患者的生命健康。分期血管成形术(SAP),即颈动脉支架置入术的一次性血管再通,通过分阶段增加患侧脑血流量,逐渐增加脑灌注压,降低支架置入后高灌注综合征的发生。
我们在此报告 2 例接受 SAP 以预防高灌注综合征的老年重度颈动脉狭窄患者。
最终诊断基于颈血管彩色多普勒超声、颈血管磁共振血管造影和脑血管数字减影血管造影。
2 例重度颈动脉狭窄患者均接受分期血管内介入治疗。
2 例患者均随访 1 年,均未发生新发脑梗死或支架再狭窄。
在治疗 SAP 时,需注意不稳定颈动脉斑块的患者可能不适合分期治疗。另外,在二期颈动脉支架置入时,需要评估动脉形态的变化并选择合适的器械。