Department of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Reconstructive, and Aesthetic Surgery, Department of Plastic, Ankara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
BMC Neurosci. 2020 Aug 17;21(1):34. doi: 10.1186/s12868-020-00584-2.
When planning nerve conduction studies using animal models, the sciatic nerve is often used and the upper extremity nerves are not preferred due to the size of laboratory animals. This study aimed to present the method and mean values of median nerve conduction studies in laboratory rabbits. Fifty-five six-month-old male New Zealand white rabbits weighing 2 to 2.5 kg were included in nerve conduction studies performed under anesthesia. The compound muscle action potential amplitude and distal latency values were recorded for the median motor nerve with the electrodes placed on the flexor digitorum superficialis muscle and tendon.
A total of 110 median nerves were evaluated. The mean amplitude of the median nerve was 30.6 ± 6.8, mV the median nerve distal latency was 1.3 ± 0.2 ms, and the mean intensity of stimulation inducing a response was 2.5 ± 1 mA.
The mean values obtained by the median motor nerve conduction method in this study can act as a guide for future nerve interventions undertaken in the upper extremities.
在使用动物模型进行神经传导研究时，通常选择坐骨神经，而不倾向于使用上肢神经，这是因为实验室动物的体型较小。本研究旨在介绍在实验室兔子中进行正中神经传导研究的方法和平均值。在麻醉下进行神经传导研究，共纳入 55 只 6 月龄、体重 2 至 2.5kg 的雄性新西兰白兔。在评估正中运动神经时，在指浅屈肌和肌腱上放置电极，记录复合肌肉动作电位幅度和远端潜伏期值。
共评估了 110 根正中神经。正中神经的平均幅度为 30.6±6.8mV，正中神经的远端潜伏期为 1.3±0.2ms，诱发反应的平均刺激强度为 2.5±1mA。
本研究中通过正中运动神经传导方法获得的平均值可作为未来在上肢进行神经干预的指导。
