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成年人听力损伤后新发抑郁障碍的风险:一项全国性回顾性队列研究。

Risk of new-onset depressive disorders after hearing impairment in adults: A nationwide retrospective cohort study.

机构信息

College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, South Korea.

College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, South Korea.

出版信息

Psychiatry Res. 2021 Jan;295:113351. doi: 10.1016/j.psychres.2020.113351. Epub 2020 Aug 14.

DOI:10.1016/j.psychres.2020.113351
PMID:32807534
Abstract

Previous studies reported that hearing impairment has been associated with depressive disorders, but little is known about the risk of newly diagnosed depression after hearing impairment diagnosed by a physician and registered with the government. We evaluated the risk of new-onset depressive disorders following hearing impairment in adults. We used data from the Korean National Health Insurance Service-National Sample Cohort and included adults with hearing impairment, and a comparison group without hearing impairment, selected by a 1:3 propensity score matching between 2004 and 2012. The dependent variable was a depressive disorder diagnosis. The hazard ratio of risk of depression was estimated using a Cox proportional hazard model. In the sample of 14,212 adults, 15.0% of people with hearing impairment (n = 3,553) experienced a depressive disorder following their hearing impairment. Those who had not experienced depression previously were more likely to develop a new-onset depressive disorder following hearing impairment than the comparison group. Male, female, old adults (60-74 years) and very-old adults (≥ 75 years) with hearing impairment were associated with an increased risk for a new-onset depressive disorders than their matched counterparts. These findings suggest a need for psychological support along with hearing rehabilitation, especially for older adults.

摘要

先前的研究报告指出,听力障碍与抑郁障碍有关,但对于医生诊断的听力障碍并在政府登记后新发抑郁障碍的风险知之甚少。我们评估了成年人听力障碍后新发抑郁障碍的风险。我们使用了韩国国家健康保险服务-国家样本队列的数据,纳入了 2004 年至 2012 年间通过倾向评分匹配(1:3)选择的听力障碍和无听力障碍的成年人。因变量是抑郁障碍的诊断。使用 Cox 比例风险模型估计风险的风险比。在 14212 名成年人的样本中,15.0%(n=3553)有听力障碍的人在听力障碍后出现抑郁障碍。与对照组相比,以前没有经历过抑郁的人更有可能在听力障碍后患上新发的抑郁障碍。听力障碍的男性、女性、老年(60-74 岁)和非常老年(≥75 岁)成年人发生新发抑郁障碍的风险高于其匹配人群。这些发现表明,除了听力康复外,还需要心理支持,特别是针对老年人。

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