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回肠造口术后再入院情况:来自新西兰一家三级中心的回顾性分析。

Re-admissions after ileostomy formation: a retrospective analysis from a New Zealand tertiary centre.

作者信息

Liu Chen, Bhat Sameer, O'Grady Gregory, Bissett Ian

机构信息

Department of Surgery, University of Auckland, Auckland, New Zealand.

出版信息

ANZ J Surg. 2020 Sep;90(9):1621-1626. doi: 10.1111/ans.16076. Epub 2020 Aug 17.

DOI:10.1111/ans.16076
PMID:32808425
Abstract

BACKGROUND

Ileostomy formation is a commonly performed procedure in colorectal surgery. The morbidity associated with ileostomies is substantial, particularly for unplanned hospital re-admissions and re-admissions with dehydration. Studies of post-ileostomy re-admissions from an Australasian institution are currently lacking. This retrospective study aimed to quantify the 60-day re-admission rate after ileostomy formation in a New Zealand tertiary centre and to determine the predictive factors.

METHODS

The surgical database of Auckland City Hospital was searched for all patients aged ≥18 years with a new ileostomy formed between first January 2015 and first January 2019. Patient electronic medical records were reviewed to obtain data regarding the primary outcome of re-admissions within 60 days of discharge, as well as patient and operative variables. Multivariate regression analysis was performed to identify independent predictors of all-cause re-admissions and re-admissions with dehydration.

RESULTS

A total of 246 patients with 266 ileostomy formations were included. The 60-day re-admission rate was 29.3%, with dehydration present in 27.0% of these re-admissions. Renal impairment at discharge (odds ratio 2.819, 95% confidence interval 1.087-7.310) and the presence of at least one Clavien-Dindo 1 complication (odds ratio 2.268, 95% confidence interval 1.301-3.954) were independently associated with all-cause re-admission. The independent predictors of re-admission with dehydration were renal impairment at discharge, codeine prescribed on discharge, Charlson Comorbidity Index and body mass index.

CONCLUSION

Unplanned hospital re-admission following ileostomy formation is a significant issue in the New Zealand patient population. Some patient groups are at particularly high risk, such as those with renal impairment at discharge.

摘要

背景

回肠造口术是结直肠手术中常见的操作。回肠造口术相关的发病率很高,尤其是计划外的再次入院以及因脱水导致的再次入院。目前缺乏来自澳大拉西亚机构的回肠造口术后再次入院情况的研究。这项回顾性研究旨在量化新西兰一家三级中心回肠造口术后60天的再次入院率,并确定预测因素。

方法

在奥克兰市医院的手术数据库中搜索2015年1月1日至2019年1月1日期间所有年龄≥18岁且新形成回肠造口的患者。查阅患者电子病历,以获取出院后60天内再次入院这一主要结局的数据,以及患者和手术变量。进行多因素回归分析以确定全因再次入院和因脱水再次入院的独立预测因素。

结果

共纳入246例患者的266次回肠造口术。60天再次入院率为29.3%,其中27.0%的再次入院患者存在脱水情况。出院时肾功能损害(比值比2.819,95%置信区间1.087 - 7.310)和至少出现1种Clavien-Dindo 1级并发症(比值比2.268,95%置信区间1.301 - 3.954)与全因再次入院独立相关。因脱水再次入院的独立预测因素为出院时肾功能损害、出院时开具可待因、Charlson合并症指数和体重指数。

结论

回肠造口术后计划外的再次入院在新西兰患者群体中是一个重要问题。一些患者群体风险特别高,比如出院时肾功能损害的患者。

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Re-admissions after ileostomy formation: a retrospective analysis from a New Zealand tertiary centre.回肠造口术后再入院情况:来自新西兰一家三级中心的回顾性分析。
ANZ J Surg. 2020 Sep;90(9):1621-1626. doi: 10.1111/ans.16076. Epub 2020 Aug 17.
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Risk factors for readmission with dehydration after ileostomy formation: A systematic review and meta-analysis.回肠造口术后因脱水再入院的风险因素:系统评价和荟萃分析。
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Readmission for dehydration or renal failure after ileostomy creation.造口术后因脱水或肾衰竭再次入院。
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Readmission After Ileostomy Creation: Retrospective Review of a Common and Significant Event.回肠造口术后再入院:对一个常见且重要事件的回顾性研究
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Acute health care resource utilization for ileostomy patients is higher than expected.回肠造口术患者的急性医疗资源利用率高于预期。
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Dehydration is the most common indication for readmission after diverting ileostomy creation.脱水是回肠造口改道术后再入院的最常见指征。
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Acute kidney injury is a common and significant complication following ileostomy formation.急性肾损伤是回肠造口术后常见且严重的并发症。
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Same-Hospital Re-Admission Rate Is Not Reliable for Measuring Post-Operative Infection-Related Re-Admission.同院再入院率不适用于衡量术后感染相关再入院情况。
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Use of an ACE inhibitor or angiotensin receptor blocker is a major risk factor for dehydration requiring readmission in the setting of a new ileostomy.使用血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂是新造回肠造口术后因脱水需要再次入院的主要危险因素。
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引用本文的文献

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Overall readmissions and readmissions related to dehydration after creation of an ileostomy: a systematic review and meta-analysis.回肠造口术后总体再入院率和与脱水相关的再入院率:系统评价和荟萃分析。
Tech Coloproctol. 2022 May;26(5):333-349. doi: 10.1007/s10151-022-02580-6. Epub 2022 Feb 22.
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Readmission after rectal resection in the ERAS-era: is a loop ileostomy the Achilles heel?在 ERAS 时代行直肠切除术后再入院:回肠袢式造口术是阿喀琉斯之踵吗?
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