一种用于γ-谷氨酰转肽酶灵敏检测和成像的双光子荧光探针。
A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase.
机构信息
Key Laboratory of Photochemical Conversion and Optoelectronic Materials and City U-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.
Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, People's Republic of China.
出版信息
Chem Commun (Camb). 2020 Sep 17;56(74):10902-10905. doi: 10.1039/d0cc02750b.
A GGT-activated two-photon fluorescent probe (4F-2CN-GSH) was developed based on a cascade reaction. 4F-2CN-GSH could selectivily detect GGT with low detection limit and distinguish ovarian cancer cells from normal cells using both one-photon and two-photon fluorescence imaging.
基于级联反应，开发了一种 GGT 激活的双光子荧光探针（4F-2CN-GSH）。4F-2CN-GSH 可以选择性地检测 GGT，检测限低，并使用单光子和双光子荧光成像来区分卵巢癌细胞和正常细胞。
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